Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTHFD1 | P11586 | 2/20 | 0.86 |
| ▸ | DHFR | P00374 | 1/20 | 0.81 |
| ▸ | SOST | Q9BQB4 | 1/20 | 0.69 |
| ▸ | MTHFD2 | P13995 | 2/20 | 0.64 |
| ▸ | LMNA | P02545 | 1/20 | 0.63 |
| ▸ | FPGS | Q05932 | 2/20 | 0.61 |
| ▸ | TYMS | P04818 | 1/20 | 0.58 |
| ▸ | ATIC | P31939 | 3/20 | 0.57 |
| ▸ | GART | P22102 | 6/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Levomefolic Acid SCHEMBL30051011 | 1.00 | MTHFD1 (0.86) | MTHFD1DHFRSOSTMTHFD2LMNA | |
| Levomefolic Acid SCHEMBL2693607 | 1.00 | MTHFD1 (0.86) | MTHFD1DHFRSOSTMTHFD2LMNA | |
| Levomefolic Acid SCHEMBL29422840 | 1.00 | MTHFD1 (0.86) | MTHFD1DHFRSOSTMTHFD2LMNA | |
| Levomefolic Acid SCHEMBL31173596 | 1.00 | MTHFD1 (0.86) | MTHFD1DHFRSOSTMTHFD2LMNA | |
| Levomefolic Acid SCHEMBL7678398 | 1.00 | MTHFD1 (0.86) | MTHFD1DHFRSOSTMTHFD2LMNA | |
| Levomefolic Acid SCHEMBL29616390 | 1.00 | MTHFD1 (0.86) | MTHFD1DHFRSOSTMTHFD2LMNA | |
| Levomefolic Acid SCHEMBL258787 | 1.00 | MTHFD1 (0.86) | MTHFD1DHFRSOSTMTHFD2LMNA | |
| Levomefolic Acid SCHEMBL1882912 | 1.00 | MTHFD1 (0.86) | MTHFD1DHFRSOSTMTHFD2LMNA | |
| Levomefolic Acid SCHEMBL4727836 | 1.00 | MTHFD1 (0.86) | MTHFD1DHFRSOSTMTHFD2LMNA | |
| Levomefolic Acid SCHEMBL30828726 | 1.00 | MTHFD1 (0.86) | MTHFD1DHFRSOSTMTHFD2LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Appears in 7308 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-122084783-A | Method for detecting content of L-5-methyltetrahydrofolate with magnesium ion interference resistance | — | 2026-05-26 | — | — | CN | claimed |
| CN-122056386-A | Moisture absorption resistant slow release microcapsule powder and preparation method and application thereof | 大连医诺生物股份有限公司 | 2026-05-19 | — | — | CN | claimed |
| CN-122030612-A | Shear-resistant slow-release microcapsule powder and preparation method and application thereof | 大连医诺生物股份有限公司 | 2026-05-15 | — | — | CN | claimed |
| US-20260132142-A1 | EGFR INHIBITOR POLYMORPH FORMS | KATMAI PHARMACEUTICALS INC (US) | 2026-05-14 | — | — | US | claimed |
| US-20260130855-A1 | GAMMA POLYGLUTAMATED ANTIFOLATES AND USES THEREOF | L E A F HOLDINGS GROUP LLC (US) | 2026-05-14 | — | — | US | claimed |
| US-20260116860-A1 | METHOD FOR PRODUCING ISOXAZOLINECARBOXYLIC ACID DERIVATIVES | BAYER AG (DE) | 2026-04-30 | — | — | US | claimed |
| US-20260117270-A1 | TETRAHYDROFOLATE METHYLTRANSFERASE MUTANT, ENCODING GENE AND APPLICATIONS THEREOF | ZHEJIANG SHENGDA BIO-PHARM CO., LTD. (CN) | 2026-04-30 | — | — | US | claimed |
| US-20260108621-A1 | Immune Cell Conjugates and Methods for Producing and Using the Same | Sandigene Inc. (US) | 2026-04-23 | — | — | US | claimed |
| EP-3523280-B1 | PROCESSES AND INTERMEDIATES FOR PREPARING A BTK INHIBITOR | JANSSEN PHARMACEUTICA NV (BE) | 2026-03-11 | — | — | EP | claimed |
| US-20260063623-A1 | METHODS OF ASSESSING METABOLIC FLUX | UNIV MICHIGAN REGENTS (US) | 2026-03-05 | — | — | US | claimed |
| EP-0539987-A2 | Process for the purification of crude alkalinic earth metal salts of N(5)-methyl-5,6,7,8-tetrahydrofolic acid | Cerbios-Pharma S.A. (CH) | 1993-05-05 | — | — | EP | claimed |
| EP-0373213-B1 | UTILIZATION OF A FOLINIC SUBSTANCE AS PLATELET ANTIAGGREGATING AGENT | SPIRAL RECHERCHE ET DEVELOPPEMENT (FR) | 1992-10-21 | — | — | EP | claimed |
| US-5153309-A | PROCESS OF MAKING TETRAHYDROPTEROYLPOLY-L-GLUTAMIC ACID DERIVATIVES | THE UNITED STATES OF AMERICA AS REPRESENTED BY THE DEPARTMENT OF HEALTH AND HUMAN SERVICES (US) | 1992-10-06 | — | — | US | claimed |
| CN-1063285-A | Process for the preparation of (6S) -and (6R) -tetrahydrofolic acid | EPROVA AG (CH) | 1992-08-05 | — | — | CN | claimed |
| EP-0495204-A1 | Process for the preparation of (6S)- and (6R)-tetrahydrofolic acid | EPROVA Aktiengesellschaft (CH) | 1992-07-22 | — | — | EP | claimed |
| US-5124452-A | Reduction of folic acid; methylation separation; purification; reducing agent stabilizer | BIORESEARCH S.P.A. (IT) | 1992-06-23 | — | — | US | claimed |
| EP-0482493-A2 | Pharmaceutical compositions active in the therapy of neurological affections in aids patients, containing as an active principle at last one compound selected from the group consisting of S-adenosyl-L-methionine salt, 5-methyl-tetrahydrofolic acid, 5-formyltetrahydrofolic acid | BIORESEARCH S.p.A. (IT) | 1992-04-29 | — | — | EP | claimed |
| WO-1992002241-A1 | A PROCESS OF MAKING TETRAHYDROPTEROYLPOLY-L-GLUTAMIC ACID DERIVATIVES | THE UNITED STATES OF AMERICA, REPRESENTED BY THE SECRETARY, UNITED STATES DEPARTMENT OF COMMERCE (US) | 1992-02-20 | — | — | WO | claimed |
| EP-0455013-A1 | Ammoniumsalts of N(5)-methyl-5,6,7,8-tetrahydrofolic acid | Cerbios-Pharma S.A. (CH) | 1991-11-06 | — | — | EP | claimed |
| US-5059595-A | PHARMACEUTICAL COMPOSITIONS CONTAINING 5-METHYLTETRAHYDROFOLIC ACID, 5-FORMYLTETRAHYDROFOLIC ACID AND THEIR PHARMACEUTICALLY ACCEPTABLE SALTS IN CONTROLLED-RELEASE FORM ACTIVE IN THE THERAPY OF ORGANIC MENTAL DISTURBANCES | BIORESEARCH, S.P.A. (IT) | 1991-10-22 | — | — | US | claimed |