Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPSR1 | Q6W5P4 | 6/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.53 |
| ▸ | LMNA | P02545 | 3/20 | 0.53 |
| ▸ | NFKB1 | P19838 | 3/20 | 0.53 |
| ▸ | TSHR | P16473 | 3/20 | 0.53 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.53 |
| ▸ | HPGD | P15428 | 2/20 | 0.53 |
| ▸ | PMP22 | Q01453 | 2/20 | 0.53 |
| ▸ | GLA | P06280 | 1/20 | 0.53 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.47 |
| ▸ | CYP2D6 | P10635 | 4/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.47 |
| ▸ | SPR | P35270 | 3/20 | 0.47 |
| ▸ | MAPT | P10636 | 3/20 | 0.47 |
| ▸ | BLM | P54132 | 3/20 | 0.47 |
| ▸ | IDO1 | P14902 | 1/20 | 0.47 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20182374 | 0.77 | NPSR1 (0.68) | NPSR1ALDH1A1LMNANFKB1TSHR | |
| SCHEMBL20182375 | 0.75 | NPSR1 (0.70) | NPSR1ALDH1A1LMNANFKB1TSHR | |
| SCHEMBL1032415 | 0.75 | NPSR1 (0.74) | NPSR1ALDH1A1LMNANFKB1TSHR | |
| SCHEMBL7657570 | 0.75 | NPSR1 (0.62) | NPSR1ALDH1A1LMNANFKB1TSHR | |
| SCHEMBL28316013 | 0.74 | NPSR1 (0.58) | NPSR1ALDH1A1LMNANFKB1TSHR | |
| SCHEMBL14790896 | 0.72 | NPSR1 (0.74) | NPSR1ALDH1A1LMNANFKB1TSHR | |
| SCHEMBL853729 | 0.72 | NPSR1 (0.68) | NPSR1ALDH1A1LMNANFKB1TSHR | |
| SCHEMBL138121 | 0.71 | NPSR1 (1.00) | NPSR1ALDH1A1LMNANFKB1TSHR | |
| SCHEMBL29350604 | 0.71 | NPSR1 (1.00) | NPSR1ALDH1A1LMNANFKB1TSHR | |
| SCHEMBL6870711 | 0.71 | MTNR1A (0.58) | NPSR1ALDH1A1LMNANFKB1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11352326-B2 | Myeloperoxidase imaging agents | THE GENERAL HOSPITAL CORPORATION (US) | 2022-06-07 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11352326-B2 | Myeloperoxidase imaging agents | MPO, CAT, EPX | NPSR1 1268/4885ALDH1A1 176/4885LMNA 4199/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.