SCHEMBL29619307

SCHEMBL29619307

O=C(O)c1cc2ccccc2c2c1C=CC(c1ccccc1)(c1ccc(N3CCCC3)cc1)O2

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
DHODH Q02127 1/20 0.43
IP6K1 Q92551 2/20 0.36
NPC1 O15118 4/20 0.36
RAB9A P51151 4/20 0.36
MAPT P10636 4/20 0.36
KMT2A Q03164 4/20 0.36
SMN1; SMN2 Q16637 3/20 0.36
PKM P14618 2/20 0.36
MEN1 O00255 2/20 0.36
KDM4E B2RXH2 2/20 0.36
ALDH1A1 P00352 1/20 0.36
LMNA P02545 1/20 0.36
TP53 P04637 1/20 0.36
HPGD P15428 1/20 0.36
ALOX15 P16050 1/20 0.36
TSHR P16473 1/20 0.36
STAT1 P42224 1/20 0.36
HSD17B10 Q99714 1/20 0.36
L3MBTL1 Q9Y468 1/20 0.36
PTPRF P10586 2/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8509702 0.93 MEN1 (0.43) DHODHNPC1RAB9AMAPTKMT2A
SCHEMBL7777302 0.89 DHODH (0.37) DHODHNPC1RAB9AMAPTKMT2A
SCHEMBL26290020 0.87 GPR35 (0.40) KMT2AMEN1KDM4EALDH1A1LMNA
SCHEMBL7936515 0.82 KEAP1 (0.42) DHODHIP6K1RAB9AMAPTKMT2A
SCHEMBL26289884 0.82 IDO1 (0.38) MAPTKMT2ASMN1; SMN2MEN1KDM4E
SCHEMBL5549293 0.80 MAPT (0.39) NPC1RAB9AMAPTKMT2ASMN1; SMN2
SCHEMBL7784131 0.80 MAPT (0.39) NPC1RAB9AMAPTKMT2ASMN1; SMN2
SCHEMBL7782083 0.79 KDM4E (0.44) NPC1RAB9AMAPTKMT2ASMN1; SMN2
SCHEMBL7473791 0.79 NPC1 (0.33) DHODHNPC1RAB9AMAPTKMT2A
SCHEMBL7785460 0.79 MAPT (0.39) DHODHNPC1RAB9AMAPTKMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11435642-B2 Smart window and method for switching the same NATIONAL SUN YAT-SEN UNIVERSITY (TW) 2022-09-06 US claimed
US-20220146873-A1 SMART WINDOW AND METHOD FOR SWITCHING THE SAME NATIONAL SUN YAT-SEN UNIVERSITY (TW) 2022-05-12 US claimed
US-11435642-B2 Smart window and method for switching the same NATIONAL SUN YAT-SEN UNIVERSITY (TW) 2022-09-06 US disclosed
US-20220146873-A1 SMART WINDOW AND METHOD FOR SWITCHING THE SAME NATIONAL SUN YAT-SEN UNIVERSITY (TW) 2022-05-12 US disclosed