Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MKNK2 | Q9HBH9 | 2/20 | 0.32 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.32 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.32 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.32 |
| ▸ | MTOR | P42345 | 1/20 | 0.31 |
| ▸ | RPTOR | Q8N122 | 1/20 | 0.31 |
| ▸ | MLST8 | Q9BVC4 | 1/20 | 0.31 |
| ▸ | KDM5B | Q9UGL1 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2969282 | 0.74 | MTOR (0.34) | MTORRPTORMLST8 | |
| SCHEMBL13097122 | 0.71 | RIPK2 (0.32) | MKNK2MAP4K4CYP3A4MTORRPTOR | |
| SCHEMBL13106048 | 0.71 | CYP46A1 (0.33) | — | |
| SCHEMBL6207995 | 0.69 | PGR (0.40) | — | |
| SCHEMBL8650400 | 0.69 | GAA (0.54) | — | |
| SCHEMBL11486255 | 0.68 | NPC1 (0.43) | CYP3A4 | |
| SCHEMBL13097121 | 0.65 | GRM4 (0.35) | CYP3A4 | |
| SCHEMBL8557122 | 0.65 | GAA (0.42) | CYP3A4 | |
| SCHEMBL4433341 | 0.62 | GAA (0.40) | SLC6A4 | |
| SCHEMBL27834563 | 0.62 | MAP4K4 (0.54) | MAP4K4MTORRPTORMLST8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100267964-A1 | N-HETEROCYCLYLPHENYL-SUBSTITUTED CYCLIC KETOENOLS | FISCHER REINER | 2010-10-21 | — | — | US | disclosed |
| US-7776791-B2 | N-heterocyclyl phenyl-substituted cyclic ketoenols | BAYER CROPSCIENCE AG (DE) | 2010-08-17 | — | — | US | disclosed |
| US-20060166829-A1 | N-Heterocycl phenyl-substituted cyclic ketoenols | BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) | 2006-07-27 | — | — | US | disclosed |
| EP-1638957-A1 | N-HETEROCYCLYL PHENYL-SUBSTITUTED CYCLIC KETOENOLS | Bayer CropScience AG (DE) | 2006-03-29 | — | — | EP | disclosed |
| WO-2004111042-A1 | N-HETEROCYCLYL PHENYL-SUBSTITUTED CYCLIC KETOENOLS | BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) | 2004-12-23 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100267964-A1 | N-HETEROCYCLYLPHENYL-SUBSTITUTED CYCLIC KETOENOLS | CYP17A1, CCNY, CCNE2 | MKNK2 1002/4885MAP4K4 714/4885CYP3A4 192/4885 |
| US-20060166829-A1 | N-Heterocycl phenyl-substituted cyclic ketoenols | WEE1, KCNE1, CCNE1 | MKNK2 1592/4885MAP4K4 1072/4885CYP3A4 69/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.