Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOS3 | P29474 | 1/20 | 0.57 |
| ▸ | NOS2 | P35228 | 1/20 | 0.57 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.47 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.47 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.47 |
| ▸ | SMARCA2 | P51531 | 1/20 | 0.44 |
| ▸ | SMARCA4 | P51532 | 1/20 | 0.44 |
| ▸ | RECQL | P46063 | 1/20 | 0.42 |
| ▸ | LOX | P28300 | 1/20 | 0.42 |
| ▸ | LOXL3 | P58215 | 1/20 | 0.42 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | CDK2 | P24941 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.40 |
| ▸ | CCNA2 | P20248 | 1/20 | 0.40 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.40 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.40 |
| ▸ | CDK5R1 | Q15078 | 1/20 | 0.40 |
| ▸ | DYRK2 | Q92630 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL119912 | 1.00 | NOS3 (0.57) | NOS3NOS2S1PR1S1PR3ADRB1 | |
| SCHEMBL3370691 | 0.87 | NOS3 (0.46) | NOS3NOS2S1PR1S1PR3ADRB1 | |
| SCHEMBL10855969 | 0.84 | RECQL (0.41) | NOS3NOS2S1PR1S1PR3ADRB1 | |
| SCHEMBL10677185 | 0.84 | RECQL (0.41) | NOS3NOS2S1PR1S1PR3ADRB1 | |
| SCHEMBL1437528 | 0.83 | RECQL (0.39) | NOS3NOS2S1PR1S1PR3ADRB1 | |
| SCHEMBL28404888 | 0.83 | NR3C1 (0.40) | NOS3NOS2S1PR1S1PR3ADRB1 | |
| SCHEMBL16446395 | 0.83 | RECQL (0.39) | NOS3NOS2S1PR1S1PR3ADRB1 | |
| SCHEMBL30595892 | 0.83 | RECQL (0.39) | NOS3NOS2S1PR1S1PR3ADRB1 | |
| SCHEMBL12989389 | 0.79 | NR3C1 (0.44) | NOS3NOS2S1PR1S1PR3SMARCA2 | |
| Ethoxycarbonyl Group SCHEMBL28282915 | 0.79 | L3MBTL1 (0.46) | NOS3NOS2S1PR1S1PR3ADRB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 34 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116425671-A | Synthesis method of 2-chloro-4- (trifluoromethyl) pyridine | 江苏省农用激素工程技术研究中心有限公司 | 2023-07-14 | — | — | CN | claimed |
| US-12583836-B2 | Sulphonamide compounds | Anaxis Pharma Pty Ltd (AU) | 2026-03-24 | — | — | US | disclosed |
| EP-4168401-B1 | SULPHONAMIDE COMPOUNDS | Anaxis Pharma Pty Ltd (AU) | 2026-01-07 | — | — | EP | disclosed |
| CN-120435228-A | Compositions comprising 4-membered cyclic carboxamide compounds | 先正达农作物保护股份公司 | 2025-08-05 | — | — | CN | disclosed |
| EP-4568746-A1 | BICYCLIC TETRAHYDROTHIAZEPINE DERIVATIVES | F. Hoffmann-La Roche AG (CH) | 2025-06-18 | — | — | EP | disclosed |
| CN-119894896-A | Inhibitors of green peroxidase | 阿斯利康(瑞典)有限公司 | 2025-04-25 | — | — | CN | disclosed |
| CN-119768401-A | Bicyclic tetrahydrothiazepine derivatives | 豪夫迈·罗氏有限公司 | 2025-04-04 | — | — | CN | disclosed |
| CN-119735584-A | Phenoxypyridine compound containing acylthiourea and heterocyclic structure, and preparation method and application thereof | 东北农业大学 | 2025-04-01 | — | — | CN | disclosed |
| CN-113272277-B | Preparation of sulfonamide herbicide process intermediates | 科迪华农业科技有限责任公司 | 2025-03-07 | — | — | CN | disclosed |
| US-20250074891-A1 | BIFUNCTIONAL SULPHONAMIDE COMPOUNDS | Anaxis Pharma Pty Ltd (AU) | 2025-03-06 | — | — | US | disclosed |
| CN-116425671-A | Synthesis method of 2-chloro-4- (trifluoromethyl) pyridine | 江苏省农用激素工程技术研究中心有限公司 | 2023-07-14 | — | — | CN | disclosed |
| CN-116056576-A | Use of strobilurin type compounds for combating phytopathogenic fungi containing F129L amino acid substitutions conferring tolerance to Qo inhibitor VIII in mitochondrial cytochrome b proteins | 巴斯夫欧洲公司 | 2023-05-02 | — | — | CN | disclosed |
| CN-115867541-A | Aminopyrimidinone derivatives | 豪夫迈·罗氏有限公司 | 2023-03-28 | — | — | CN | disclosed |
| CN-115803025-A | Non-lysosomal glucosylceramidase inhibitors and uses thereof | 阿勒克图治疗公司 | 2023-03-14 | — | — | CN | disclosed |
| CN-109641854-B | Modulators of integrated stress pathways | 卡里科生命科学有限责任公司 | 2023-02-03 | — | — | CN | disclosed |
| CN-115385852-A | Efficient synthesis method of 2-amino-4-trifluoromethylpyridine | 湖南阿斯迪康药业有限公司 | 2022-11-25 | — | — | CN | disclosed |
| CN-110669052-B | Substituted 2-azabicyclic compounds and their use as orexin receptor modulators | 詹森药业有限公司 | 2022-10-11 | — | — | CN | disclosed |
| EP-4038068-A1 | N-SUBSTITUTED-4-OXO-3,4-DIHYDROPYRIDO[2,3-D]PYRIMIDIN-2-YL DERIVATIVES AS INHIBITORS OF THE HUMAN IMMUNODEFICIENCY VIRUS REPLICATION | VIIV Healthcare UK (No.5) Limited (GB) | 2022-08-10 | — | — | EP | disclosed |
| CN-110998769-B | Dye-sensitized photoelectric conversion element | 日本精工株式会社 | 2022-07-01 | — | — | CN | disclosed |
| CN-108368064-B | 1,2, 3-triazole derivative and insecticide and acaricide comprising the same as active ingredient | 北兴化学工业株式会社 | 2022-04-26 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20250074891-A1 | BIFUNCTIONAL SULPHONAMIDE COMPOUNDS | MLKL, RIPK3, CASP9 | NOS3 542/4885NOS2 489/4885S1PR1 2617/4885 |
| US-12583836-B2 | Sulphonamide compounds | MLKL, RIPK3, CASP1 | NOS3 246/4885NOS2 504/4885S1PR1 454/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.