Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB | P10828 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 3/20 | 0.40 |
| ▸ | SLC22A6 | Q4U2R8 | 2/20 | 0.40 |
| ▸ | TSHR | P16473 | 5/20 | 0.39 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.39 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.39 |
| ▸ | CAMK2A | Q9UQM7 | 1/20 | 0.36 |
| ▸ | HDAC11 | Q96DB2 | 3/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | GABRR3 | A8MPY1 | 1/20 | 0.34 |
| ▸ | GABRP | O00591 | 1/20 | 0.34 |
| ▸ | GABRD | O14764 | 1/20 | 0.34 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.34 |
| ▸ | GABBR2 | O75899 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.34 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.34 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.34 |
| ▸ | GABRR1 | P24046 | 1/20 | 0.34 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23788204 | 1.00 | THRB (0.41) | THRBLMNASLC22A6TSHRNFKB1 | |
| SCHEMBL5150321 | 1.00 | THRB (0.41) | THRBLMNASLC22A6TSHRNFKB1 | |
| SCHEMBL4612734 | 1.00 | THRB (0.41) | THRBLMNASLC22A6TSHRNFKB1 | |
| SCHEMBL29628869 | 1.00 | THRB (0.41) | THRBLMNASLC22A6TSHRNFKB1 | |
| SCHEMBL23788205 | 0.98 | LMNA (0.42) | THRBLMNASLC22A6TSHRNFKB1 | |
| SCHEMBL8817428 | 0.94 | LMNA (0.44) | THRBLMNASLC22A6TSHRNFKB1 | |
| SCHEMBL23788019 | 0.92 | TSHR (0.46) | THRBLMNASLC22A6TSHRNFKB1 | |
| SCHEMBL9449787 | 0.92 | TSHR (0.46) | THRBLMNASLC22A6TSHRNFKB1 | |
| SCHEMBL23788184 | 0.92 | TSHR (0.46) | THRBLMNASLC22A6TSHRNFKB1 | |
| SCHEMBL7884128 | 0.92 | TSHR (0.46) | THRBLMNASLC22A6TSHRNFKB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11918645-B2 | Vaccines against hepatitis B virus | ALTIMMUNE UK LIMITED (GB) | 2024-03-05 | — | — | US | disclosed |
| US-20240042007-A1 | Fluorocarbon-Linked Peptide Formulation | ALTIMMUNE UK LTD (GB) | 2024-02-08 | — | — | US | disclosed |
| US-11648305-B2 | Fluorocarbon-linked peptide formulation | Altimmune UK Ltd. (GB) | 2023-05-16 | — | — | US | disclosed |
| US-20230090379-A1 | VACCINES AGAINST HEPATITIS B VIRUS | ALTIMMUNE UK LIMITED (GB) | 2023-03-23 | — | — | US | disclosed |
| US-11382969-B2 | Vaccines against Hepatitis B virus | ALTIMMUNE UK LTD (GB) | 2022-07-12 | — | — | US | disclosed |
| EP-3995146-A1 | VACCINES AGAINST HEPATITIS B VIRUS | ALTIMMUNE UK LIMITED (GB) | 2022-05-11 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230090379-A1 | VACCINES AGAINST HEPATITIS B VIRUS | HLA-DRB1, CD4, HLA-B | THRB 457/4885LMNA 2272/4885SLC22A6 2355/4885 |
| US-11918645-B2 | Vaccines against hepatitis B virus | HLA-DRB1, CD4, HLA-B | THRB 457/4885LMNA 2272/4885SLC22A6 2355/4885 |
| US-11382969-B2 | Vaccines against Hepatitis B virus | CD4, HLA-DRB1, HLA-B | THRB 425/4885LMNA 2172/4885SLC22A6 2383/4885 |
| US-20240042007-A1 | Fluorocarbon-Linked Peptide Formulation | VIP, FGB, LNPEP | THRB 3856/4885LMNA 442/4885SLC22A6 1165/4885 |
| US-11648305-B2 | Fluorocarbon-linked peptide formulation | VIP, FGB, LNPEP | THRB 3856/4885LMNA 442/4885SLC22A6 1165/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.