Cadaverine Tartrate

Cadaverine Tartrate

SCHEMBL2963333

CCOCC.O=C(O)C(O)C(O)C(=O)O

nearest known ligand 0.56

Full drug profile on Sugi Atlas →

Known targets — ChEMBL curated mechanism

ADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB1ADRB2ADRB3CHRM1CHRM2CHRM3CHRM4ESR1ESR2GABRA1GABRB1GABRG2GBA1HRH1HTR1DHTR2AOPRD1OPRK1OPRM1SLC6A2SLC6A3TUBA1ATUBA1BTUBA1CTUBA3CTUBA3ETUBA4ATUBBTUBB1TUBB2ATUBB2BTUBB3TUBB4ATUBB4BTUBB6TUBB8rplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO

The experimentally established mechanism targets of Cadaverine Tartrate. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CHRM1 known ✓ P11229 1/20 0.36
CHRM3 known ✓ P20309 1/20 0.36
HTR2A known ✓ P28223 1/20 0.36
ADRA1A known ✓ P35348 1/20 0.36
HRH1 known ✓ P35367 1/20 0.36
SLC6A3 known ✓ Q01959 1/20 0.36
TSHR P16473 4/20 0.56
TP53 P04637 1/20 0.38
ALDH1A1 P00352 2/20 0.37
CYP2C9 P11712 1/20 0.37
PDE4A P27815 1/20 0.37
PGD P52209 2/20 0.37
AKR1A1 P14550 1/20 0.36
HTR2C P28335 1/20 0.36
DRD3 P35462 1/20 0.36
HDAC1 Q13547 1/20 0.36
HDAC2 Q92769 1/20 0.36
TDP1 Q9NUW8 1/20 0.36
NFKB1 P19838 1/20 0.35
CYP2C19 P33261 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Ether SCHEMBL7748926 0.89 TSHR (0.43) TSHRALDH1A1
Cadaverine Tartrate SCHEMBL2959190 0.87 ALDH1A1 (0.52) TSHRALDH1A1CYP2C9PDE4AOR51E2
Lactic Acid SCHEMBL1237356 0.83 TP53 (0.61) TSHRTP53ALDH1A1CHRM1AKR1A1
Ether SCHEMBL9389158 0.83 TP53 (0.38) TSHRTP53ALDH1A1CHRM1AKR1A1
Cadaverine Tartrate SCHEMBL18987140 0.82 TSHR (0.71) TSHRTP53CYP2C9PDE4ACHRM1
Lactic Acid SCHEMBL8930737 0.81 TP53 (0.58) TSHRTP53ALDH1A1CHRM1AKR1A1
SCHEMBL2959251 0.80 TSHR (0.52) TSHRALDH1A1
Cadaverine Tartrate SCHEMBL2958605 0.80 ALDH1A1 (0.56) TSHRALDH1A1CYP2C9PDE4A
Ether SCHEMBL8206941 0.80 TP53 (0.40) TSHRTP53ALDH1A1CHRM1AKR1A1
Cadaverine Tartrate SCHEMBL282045 0.79 TSHR (0.67) TSHRTP53ALDH1A1CYP2C9PDE4A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 21 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6329189-B1 FOR CATALYZING REACTION BETWEEN AN EPOXY RING OF AN EPOXYSUCCINIC ACID AND PHENOLIC HYDROXYL GROUP OF FLAVONOID, OR A FLAVONOID ANALOGOUS COMPOUND TO FORM TARTARIC ACID ETHER WHICH IS USED IN FOOD AND DRUG INDUSTRY KIKKOMAN CORPORATION (JP) 2001-12-11 US claimed
JP-11308990-A None JP disclosed
JP-11308990-A None JP disclosed
US-9630905-B2 Amphiphilic macromolecules and methods of use thereof RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY (US) 2017-04-25 US disclosed
US-20160068467-A1 AMPHIPHILIC MACROMOLECULES AND METHODS OF USE THEREOF RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY (US) 2016-03-10 US disclosed
US-7766978-B2 Acidic hair dyeing method KOKYU ALCOHOL KOGYO CO., LTD. (JP) 2010-08-03 US disclosed
US-20090100609-A1 ACIDIC HAIR DYE COMPOSITION KOKYU ALCOHOL KOGYO CO., LTD. (JP) 2009-04-23 US disclosed
EP-1142963-B1 Use of tartaric acid diesters as biodegradable surfactants AIR PROD & CHEM (US) 2006-03-15 EP disclosed
CN-1203841-C Effervescent base GERGELY GERHARD (AT) 2005-06-01 CN disclosed
US-6585814-B2 Hydrocarbon solvent free, aqueous coatings, inks, adhesives and agricultural agents AIR PRODUCTS AND CHEMICALS, INC. 2003-07-01 US disclosed
US-20030033957-A1 Tartaric acid diesters as biodegradable surfactants SLONE CAROLINE SASSANO (US) 2003-02-20 US disclosed
US-20030008943-A1 Tartaric acid diesters as biodegradable surfactants SLONE CAROLINE SASSANO (US) 2003-01-09 US disclosed
US-6423376-B1 COATING A WATER BASED COMPOSITE FREE OF HYDROCARBON SOLVENT TO SURFACE, REDUCING THE SURFACE TENSION AIR PRODUCTS AND CHEMICALS, INC. 2002-07-23 US disclosed
US-6329189-B1 FOR CATALYZING REACTION BETWEEN AN EPOXY RING OF AN EPOXYSUCCINIC ACID AND PHENOLIC HYDROXYL GROUP OF FLAVONOID, OR A FLAVONOID ANALOGOUS COMPOUND TO FORM TARTARIC ACID ETHER WHICH IS USED IN FOOD AND DRUG INDUSTRY KIKKOMAN CORPORATION (JP) 2001-12-11 US disclosed
US-6329189-B1 FOR CATALYZING REACTION BETWEEN AN EPOXY RING OF AN EPOXYSUCCINIC ACID AND PHENOLIC HYDROXYL GROUP OF FLAVONOID, OR A FLAVONOID ANALOGOUS COMPOUND TO FORM TARTARIC ACID ETHER WHICH IS USED IN FOOD AND DRUG INDUSTRY KIKKOMAN CORPORATION (JP) 2001-12-11 US disclosed
US-6329189-B1 FOR CATALYZING REACTION BETWEEN AN EPOXY RING OF AN EPOXYSUCCINIC ACID AND PHENOLIC HYDROXYL GROUP OF FLAVONOID, OR A FLAVONOID ANALOGOUS COMPOUND TO FORM TARTARIC ACID ETHER WHICH IS USED IN FOOD AND DRUG INDUSTRY KIKKOMAN CORPORATION (JP) 2001-12-11 US disclosed
EP-1142963-A1 Tartaric acid diesters as biogradable surfactants AIR PRODUCTS AND CHEMICALS, INC. (US) 2001-10-10 EP disclosed
CN-1276716-A Effervescent base GERGELY GERHARD (AT) 2000-12-13 CN disclosed
JP-H11308990-A NEW TARTARIC ACID ETHER COMPOUND-PRODUCTIVE ENZYME, PRODUCTION OF TARTARIC ACID ETHER COMPOUND USING THE SAME, AND NEW TARTARIC ACID ETHER COMPOUND KIKKOMAN CORP 1999-11-09 JP disclosed
JP-H11308990-A NEW TARTARIC ACID ETHER COMPOUND-PRODUCTIVE ENZYME, PRODUCTION OF TARTARIC ACID ETHER COMPOUND USING THE SAME, AND NEW TARTARIC ACID ETHER COMPOUND KIKKOMAN CORP 1999-11-09 JP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090100609-A1 ACIDIC HAIR DYE COMPOSITION H1-0, MRM1, H1-4 CHRM1 946/4885CHRM3 3295/4885HTR2A 2456/4885
US-20160068467-A1 AMPHIPHILIC MACROMOLECULES AND METHODS OF USE THEREOF ZYX, APOB, MSR1 CHRM1 1171/4885CHRM3 2496/4885HTR2A 3967/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.