Known targets — ChEMBL curated mechanism
ABCC9ABL1ACEACHEACVR1ADORA1ADORA2AADORA2BADORA3ADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB1ADRB2ADRB3AGTR1ALOX5ATP4AATP4BBCRBTKCACNA1ACACNA1BCACNA1CCACNA1DCACNA1ECACNA1FCACNA1GCACNA1HCACNA1ICACNA1SCACNA2D1CACNA2D2CACNA2D3CACNA2D4CACNB1CACNB2CACNB3CACNB4CACNG1CACNG2CACNG3CACNG4CACNG5CACNG6CACNG7CACNG8CALCRLCFBCHRM1CHRM2CHRM3CHRM4CHRM5CHRNA1CHRNB1CHRNDCHRNECHRNGCRBNCUL4ACXCR1CXCR2DDB1DDCDHFRDPP4DRD2DRD3DRD4EGFRERBB2ERBB4ESR1ESR2FDPSFKBP1AFLT1FLT3FLT4GARTGHSRGRIA1GRIA2GRIA3GRIA4GRIK1GRIK2GRIK3GRIK4GRIK5GRIN2AGSK3AGSK3BHDAC1HDAC10HDAC11HDAC2HDAC3HDAC4HDAC5HDAC6HDAC7HDAC8HDAC9HRH1HTR1AHTR1BHTR1DHTR1EHTR1FHTR2AHTR2BHTR2CHTR3AHTR3BHTR3CHTR3DHTR3EHTR4HTR5AHTR6HTR7IDH1IDH2IMPA1ITGA2BITGB3JAK1JAK2JAK3KCNJ11KCNK3KCNK9KDRKITMEN1METMMP1MMP13MMP7MMP8NANOD2NS5bODC1OPG057OPRD1OPRK1OPRM1PPARP1PARP2PDE3APDE3BPDE4APDE4BPDE4CPDE4DPDGFRBPIK3CAPIK3CBPIK3CDPIK3CGPIK3R1PIK3R2PIK3R3PIK3R5PKLRPPARDPPATPTGS1PTGS2RBX1ROCK1ROCK2RRM1RRM2RRM2BSCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASCNN1ASCNN1BSCNN1GSIGMAR1SLC10A2SLC5A2SLC6A2SLC6A3SLC6A4SLC9A3SYKTACR1THRATHRBTOP1TUBA1ATUBA1BTUBA1CTUBA3CTUBA3ETUBA4ATUBBTUBB1TUBB2ATUBB2BTUBB3TUBB4ATUBB4BTUBB6TUBB8TYK2TYMSVDRampCblablaT-3blaT-4blaT-5blaT-6blaUOE-1dacAdacBdacCfolAfolPftsIgyrAgyrBileSmecAmrcAmrcBmrdAparCparEpbp2pbp4pbpApbpFrplArplBrplCrplDrplErplFrplIrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmE2rpmFrpmGrpmG1rpmG2rpmG3rpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUthyAykgMykgO
The experimentally established mechanism targets of Adenosine Triphosphate. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRB2 known ✓ | P07550 | 1/20 | 0.72 |
| ▸ | ADORA1 known ✓ | P30542 | 1/20 | 0.72 |
| ▸ | PDE4D known ✓ | Q08499 | 1/20 | 0.72 |
| ▸ | PDE3A known ✓ | Q14432 | 1/20 | 0.72 |
| ▸ | P2RY1 | P47900 | 10/20 | 0.81 |
| ▸ | P2RY2 | P41231 | 3/20 | 0.81 |
| ▸ | P2RX1 | P51575 | 2/20 | 0.81 |
| ▸ | P2RX3 | P56373 | 2/20 | 0.81 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.81 |
| ▸ | SRC | P12931 | 2/20 | 0.81 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.81 |
| ▸ | P2RX4 | Q99571 | 1/20 | 0.81 |
| ▸ | P2RX2 | Q9UBL9 | 1/20 | 0.81 |
| ▸ | TRPM2 | O94759 | 2/20 | 0.76 |
| ▸ | MACROD2 | A1Z1Q3 | 1/20 | 0.76 |
| ▸ | SIRT6 | Q8N6T7 | 1/20 | 0.76 |
| ▸ | MACROD1 | Q9BQ69 | 1/20 | 0.76 |
| ▸ | P2RY11 | Q96G91 | 2/20 | 0.72 |
| ▸ | ENPP1 | P22413 | 1/20 | 0.72 |
| ▸ | DNPH1 | O43598 | 1/20 | 0.72 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Adenosine Triphosphate SCHEMBL29392565 | 1.00 | P2RY1 (0.81) | P2RY1P2RY2P2RX1P2RX3ALDH1A1 | |
| Adenosine Triphosphate SCHEMBL574960 | 0.99 | P2RY1 (0.83) | P2RY1P2RY2P2RX1P2RX3ALDH1A1 | |
| Adenosine Triphosphate SCHEMBL29663097 | 0.99 | P2RY1 (0.83) | P2RY1P2RY2P2RX1P2RX3ALDH1A1 | |
| Adenosine Triphosphate SCHEMBL29573857 | 0.99 | P2RY1 (0.83) | P2RY1P2RY2P2RX1P2RX3ALDH1A1 | |
| Adenosine Triphosphate SCHEMBL19947525 | 0.97 | P2RY1 (0.83) | P2RY1P2RY2P2RX1P2RX3ALDH1A1 | |
| Adenosine Diphosphate SCHEMBL30929365 | 0.95 | P2RY1 (0.87) | P2RY1P2RY2P2RX1P2RX3ALDH1A1 | |
| Adenosine Diphosphate SCHEMBL5498270 | 0.95 | P2RY1 (0.87) | P2RY1P2RY2P2RX1P2RX3ALDH1A1 | |
| Adenosine Diphosphate SCHEMBL31158049 | 0.95 | P2RY1 (0.87) | P2RY1P2RY2P2RX1P2RX3ALDH1A1 | |
| Adenosine Triphosphate SCHEMBL3498802 | 0.94 | P2RY1 (0.77) | P2RY1P2RY2P2RX1P2RX3ALDH1A1 | |
| Adenosine Triphosphate SCHEMBL3840392 | 0.94 | P2RY1 (0.77) | P2RY1P2RY2P2RX1P2RX3ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4638744-A1 | OLIGONUCLEOTIDE FRAGMENTS AND METHODS OF MAKING RNAI AGENTS USING THE SAME | Eli Lilly and Company (US) | 2025-10-29 | — | — | EP | disclosed |
| CN-118853828-A | ATP (adenosine triphosphate) detection test strip based on DNA tetrahedron and preparation and detection methods thereof | 山东大学 | 2024-10-29 | — | — | CN | disclosed |
| WO-2024137622-A9 | OLIGONUCLEOTIDE FRAGMENTS AND METHODS OF MAKING RNAI AGENTS USING THE SAME | ELI LILLY AND COMPANY (US) | 2024-07-25 | — | — | WO | disclosed |
| WO-2024137622-A1 | OLIGONUCLEOTIDE FRAGMENTS AND METHODS OF MAKING RNAI AGENTS USING THE SAME | ELI LILLY AND COMPANY (US) | 2024-06-27 | — | — | WO | disclosed |
| CN-109890375-B | Cellular ATP-dependent antiporter inhibitors and methods for producing same | 塔克西姆农业制作联合股份公司 | 2022-03-22 | — | — | CN | disclosed |