Adenosine Triphosphate

Adenosine Triphosphate

SCHEMBL574960

Nc1ncnc2c1ncn2[C@@H]1O[C@H](COP(=O)(O)OP(=O)([O-])OP(=O)([O-])O)[C@@H](O)[C@H]1O.[Na+].[Na+]

nearest known ligand 0.83

Full drug profile on Sugi Atlas →

Known targets — ChEMBL curated mechanism

ABCC8ACEADORA1ADORA2AADORA2BADORA3ALDH5A1ALOX5ALOX5APATP4AATP4BBRAFCA1CA12CA2CA4CYSLTR1DHFRDPEP1EDNRAEDNRBESR2F10FDPSFGF1GABBR1GABBR2GABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGARTGNRHRGSC1HMGCRIMPDH1IMPDH2KCNJ11LY96NOD2NR3C1NS3NS4ANS5bP2RY1P2RY12P2RY2P2RY4P2RY6PBP2XPDE3APDE3BPDE4APDE4BPDE4CPDE4DPDK1PDK2PDK3PDK4PPARGPPATPTGIRPTGS1PTGS2RAF1RYR1RYR3SCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASERPINC1SLC12A1SLC12A3SYKTHRATHRBTLR3TLR4TLR9TUBA1ATUBA1BTUBA1CTUBA3CTUBA3ETUBA4ATUBBTUBB1TUBB2ATUBB2BTUBB3TUBB4ATUBB4BTUBB6TUBB8TYMSVKORC1XDHblablaIMP-1blaOXA-33blaOXA-58blaT-3blaT-4blaT-5blaT-6dacAdacBdacCfolAfolPfolP1ftsIfusAgaggyrAgyrBmecAmrcAmrcBmrdApbp1apbp1bpbp2pbp2apbp2bpbp3pbp4pbpApbpBpbpCpbpFpolponBrplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpoArpoBrpoCrpoZrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO

The experimentally established mechanism targets of Adenosine Triphosphate. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
P2RY1 known ✓ P47900 10/20 0.83
P2RY2 known ✓ P41231 3/20 0.83
ADORA1 known ✓ P30542 1/20 0.73
PDE4D known ✓ Q08499 1/20 0.73
PDE3A known ✓ Q14432 1/20 0.73
P2RX1 P51575 2/20 0.83
P2RX3 P56373 2/20 0.83
ALDH1A1 P00352 2/20 0.83
SRC P12931 2/20 0.83
SMN1; SMN2 Q16637 2/20 0.83
P2RX4 Q99571 1/20 0.83
P2RX2 Q9UBL9 1/20 0.83
TRPM2 O94759 2/20 0.77
MACROD2 A1Z1Q3 1/20 0.77
SIRT6 Q8N6T7 1/20 0.77
MACROD1 Q9BQ69 1/20 0.77
P2RY11 Q96G91 2/20 0.73
ENPP1 P22413 1/20 0.73
TAS1R3 Q7RTX0 2/20 0.73
TAS1R1 Q7RTX1 2/20 0.73

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Adenosine Triphosphate SCHEMBL29573857 1.00 P2RY1 (0.83) P2RY1P2RY2P2RX1P2RX3ALDH1A1
Adenosine Triphosphate SCHEMBL29663097 1.00 P2RY1 (0.83) P2RY1P2RY2P2RX1P2RX3ALDH1A1
Adenosine Triphosphate SCHEMBL29392565 0.99 P2RY1 (0.81) P2RY1P2RY2P2RX1P2RX3ALDH1A1
Adenosine Triphosphate SCHEMBL29636841 0.99 P2RY1 (0.81) P2RY1P2RY2P2RX1P2RX3ALDH1A1
Adenosine Triphosphate SCHEMBL19947525 0.98 P2RY1 (0.83) P2RY1P2RY2P2RX1P2RX3ALDH1A1
Adenosine Diphosphate SCHEMBL31158049 0.95 P2RY1 (0.87) P2RY1P2RY2P2RX1P2RX3ALDH1A1
Adenosine Diphosphate SCHEMBL30929365 0.95 P2RY1 (0.87) P2RY1P2RY2P2RX1P2RX3ALDH1A1
Adenosine Diphosphate SCHEMBL5498270 0.95 P2RY1 (0.87) P2RY1P2RY2P2RX1P2RX3ALDH1A1
Adenosine Triphosphate SCHEMBL29467395 0.95 P2RY1 (0.89) P2RY1P2RY2P2RX1P2RX3ALDH1A1
Adenosine Triphosphate SCHEMBL1496208 0.95 P2RY1 (0.89) P2RY1P2RY2P2RX1P2RX3ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 225 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3406729-B1 METHOD FOR ENZYMATIC PREPARATION OF FLUDARABINE PHOSPHATE ZHEJIANG HISUN PHARM CO LTD (CN) 2025-09-17 EP claimed
US-12350388-B2 Methods for measuring and quantifying surface cleanability of articles B/E AEROSPACE, INC. (US) 2025-07-08 US claimed
EP-4148420-B1 METHODS FOR MEASURING AND QUANTIFYING SURFACE CLEANABILITY OF ARTICLES BE AEROSPACE INC (US) 2025-06-11 EP claimed
CN-119639715-A Nicotinamide mononucleotide adenyltransferase mutant and application thereof 浙江工业大学 2025-03-18 CN claimed
WO-2024178428-A9 SHELF STABLE ORGANIC NUCLEOTIDE COMPOSITIONS AND METHODS OF MANUFACTURING THE SAME Glanbia Nutritionals, Inc. (US) 2024-10-24 WO claimed
WO-2024178428-A1 SHELF STABLE ORGANIC NUCLEOTIDE COMPOSITIONS AND METHODS OF MANUFACTURING THE SAME Glanbia Nutritionals, Inc. (US) 2024-08-29 WO claimed
US-20240285541-A1 SHELF STABLE ORGANIC NUCLEOTIDE COMPOSITIONS AND METHODS OF MANUFACTURING THE SAME Glanbia Nutritionals, Inc. (US) 2024-08-29 US claimed
CN-117467718-A Method for preparing pyridoxal 5' -phosphate 湖北远大生物技术有限公司 2024-01-30 CN claimed
CN-116064466-A High-density fermentation process of nicotinamide riboside kinase and application of nicotinamide riboside kinase in NMN production 江西海文生物科技有限公司 2023-05-05 CN claimed
WO-2023040205-A1 METHOD FOR EFFICIENTLY PREPARING NICOTINAMIDE MONONUCLEOTIDE AND FUSION PROTEIN 湖北远大生命科学与技术有限责任公司 2023-03-23 WO claimed
US-20230077611-A1 METHODS FOR MEASURING AND QUANTIFYING SURFACE CLEANABILITY OF ARTICLES B/E AEROSPACE, INC. 2023-03-16 US claimed
EP-4148420-A1 METHODS FOR MEASURING AND QUANTIFYING SURFACE CLEANABILITY OF ARTICLES B/E Aerospace, Inc. (US) 2023-03-15 EP claimed
CN-115637262-A Method for efficiently preparing nicotinamide mononucleotide and fusion protein 湖北远大生命科学与技术有限责任公司 2023-01-24 CN claimed
EP-3962493-A2 METHODS OF MODULATING IMMUNE ACTIVITY/LEVEL OF IRF OR STING OR OF TREATING CANCER, COMPRISING THE ADMINISTRATION OF A STING MODULATOR AND/OR PURINERGIC RECEPTOR MODULATOR OR POSTCELLULAR SIGNALING FACTOR Flagship Pioneering Innovations V, Inc. (US) 2022-03-09 EP claimed
US-12617811-B2 HPK1 inhibitors and uses thereof REGOR PHARMACEUTICALS, INC. (US) 2026-05-05 US disclosed
US-12612424-B2 HPK1 inhibitors and uses thereof REGOR PHARMACEUTICALS, INC. (US) 2026-04-28 US disclosed
EP-4717695-A1 CRYSTAL FORM AND SALT FORM OF FIVE- AND SIX-MEMBERED COMPOUND, PREPARATION METHOD, PHARMACEUTICAL COMPOSITION, AND USE Hangzhou Polymed Biopharmaceuticals, Inc. (CN) 2026-04-01 EP disclosed
CN-103110602-A Disodium adenosine triphosphate troche medical composition CHENGDU TIANTAISHAN PHARMACEUTICAL CO LTD 2013-05-22 CN disclosed
CN-102449168-A Genotoxicity testing GENTRONIX LTD 2012-05-09 CN disclosed
US-20120035079-A1 GENOTOXICITY TESTING GENTRONIX LIMITED (GB) 2012-02-09 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12612424-B2 HPK1 inhibitors and uses thereof NEK11, NEK1, CSNK1A1 P2RY1 2863/4885P2RY2 3576/4885ADORA1 1318/4885
US-12617811-B2 HPK1 inhibitors and uses thereof MAP2K4, MAP2K1, MAP2K3 P2RY1 2707/4885P2RY2 3047/4885ADORA1 4821/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.