Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABRA1 | P14867 | 1/20 | 0.39 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.39 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.39 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.39 |
| ▸ | PIK3CA | P42336 | 3/20 | 0.37 |
| ▸ | PRKDC | P78527 | 3/20 | 0.37 |
| ▸ | RET | P07949 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | PKM | P14618 | 2/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | TYK2 | P29597 | 4/20 | 0.34 |
| ▸ | MTOR | P42345 | 2/20 | 0.33 |
| ▸ | TDP2 | O95551 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 2/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | CCR6 | P51684 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29638310 | 0.91 | ALDH1A1 (0.40) | PIK3CAPRKDCRETMAPTALDH1A1 | |
| SCHEMBL29638472 | 0.87 | POLB (0.39) | GABRA1GABRG2GABRB3GABRA3PIK3CA | |
| SCHEMBL24557273 | 0.85 | MAPT (0.39) | PIK3CAMAPTTYK2 | |
| SCHEMBL29638466 | 0.85 | MAPT (0.39) | PIK3CAMAPTTYK2 | |
| SCHEMBL29638437 | 0.84 | HPGD (0.40) | MAPTALDH1A1TYK2HTTMEN1 | |
| SCHEMBL24557258 | 0.84 | NPC1 (0.41) | MAPTALDH1A1POLBTYK2MEN1 | |
| SCHEMBL29638464 | 0.84 | NPC1 (0.41) | MAPTALDH1A1POLBTYK2MEN1 | |
| SCHEMBL29638468 | 0.83 | TRPV1 (0.39) | MAPTTYK2SMN1; SMN2 | |
| SCHEMBL29638414 | 0.83 | TYK2 (0.35) | MAPTPOLBTYK2HPGD | |
| SCHEMBL24557281 | 0.82 | KMT2A (0.39) | MAPTALDH1A1POLBTYK2MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022136914-A1 | TYK2 INHIBITORS AND USES THEREOF | SUDO BIOSCIENCES LIMITED (GB) | 2022-06-30 | — | — | WO | disclosed |