Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | AMD1 | P17707 | 1/20 | 0.36 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.34 |
| ▸ | MAP4K1 | Q92918 | 9/20 | 0.33 |
| ▸ | TYK2 | P29597 | 2/20 | 0.33 |
| ▸ | IDH1 | O75874 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.32 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.32 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.32 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.32 |
| ▸ | FADS1 | O60427 | 1/20 | 0.31 |
| ▸ | LYN | P07948 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24557273 | 1.00 | MAPT (0.39) | MAPTAMD1KDM4CMAP4K1TYK2 | |
| SCHEMBL29638472 | 0.89 | POLB (0.39) | MAPTTYK2IDH1MAPK1PIK3CA | |
| SCHEMBL29638468 | 0.88 | TRPV1 (0.39) | MAPTTYK2 | |
| SCHEMBL29638345 | 0.85 | GABRA1 (0.39) | MAPTTYK2PIK3CA | |
| SCHEMBL29638437 | 0.83 | HPGD (0.40) | MAPTTYK2 | |
| SCHEMBL24557258 | 0.82 | NPC1 (0.41) | MAPTTYK2TSHRLYN | |
| SCHEMBL29638464 | 0.82 | NPC1 (0.41) | MAPTTYK2TSHRLYN | |
| SCHEMBL24557251 | 0.82 | JAK2 (0.37) | MAPTTYK2IDH1PIK3CALYN | |
| SCHEMBL29638415 | 0.82 | JAK2 (0.37) | MAPTTYK2IDH1PIK3CALYN | |
| SCHEMBL24557356 | 0.82 | PHGDH (0.36) | TYK2MAPK1PIK3CA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022136914-A1 | TYK2 INHIBITORS AND USES THEREOF | SUDO BIOSCIENCES LIMITED (GB) | 2022-06-30 | — | — | WO | disclosed |