SCHEMBL29639366

SCHEMBL29639366

NC(=S)Nc1ccc(F)cc1F

nearest known ligand 0.60

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 1/20 0.53
HTT P42858 3/20 0.51
ALDH1A1 P00352 4/20 0.49
SMN1; SMN2 Q16637 2/20 0.49
NPC1 O15118 2/20 0.49
CYP2C19 P33261 2/20 0.49
RAB9A P51151 1/20 0.49
KDM4E B2RXH2 1/20 0.48
MAPT P10636 1/20 0.48
PKM P14618 1/20 0.48
MAPK1 P28482 1/20 0.48
L3MBTL1 Q9Y468 1/20 0.48
CACNA1B Q00975 1/20 0.47
APBA1 Q02410 1/20 0.47
KMT2A Q03164 1/20 0.46
CA12 O43570 1/20 0.45
CA1 P00915 1/20 0.45
CA2 P00918 1/20 0.45
CA9 Q16790 1/20 0.45
CYP1A2 P05177 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL140667 1.00 LMNA (0.53) LMNAHTTALDH1A1SMN1; SMN2NPC1
SCHEMBL30542253 0.84 SMN1; SMN2 (0.49) LMNAHTTALDH1A1SMN1; SMN2CYP2C19
SCHEMBL145336 0.84 SMN1; SMN2 (0.49) LMNAHTTALDH1A1SMN1; SMN2CYP2C19
SCHEMBL5814377 0.82 HTT (0.54) LMNAHTTALDH1A1SMN1; SMN2NPC1
SCHEMBL5525050 0.81 SIGMAR1 (0.50) LMNAALDH1A1KDM4EMAPTL3MBTL1
SCHEMBL28880172 0.81 L3MBTL1 (0.56) LMNAALDH1A1SMN1; SMN2NPC1CYP2C19
SCHEMBL6833378 0.81 POLB (0.51) ALDH1A1NPC1MAPTKMT2A
SCHEMBL29586280 0.81 GAA (0.53) LMNAHTTALDH1A1KDM4EMAPT
SCHEMBL28563284 0.81 LMNA (0.58) LMNAHTTALDH1A1SMN1; SMN2NPC1
SCHEMBL24356073 0.80 HTT (0.56) LMNAHTTALDH1A1SMN1; SMN2NPC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118704008-A Copper etching solution for packaging circuit substrate and preparation method and application thereof 浙江奥首材料科技有限公司 2024-09-27 CN claimed
CN-114432901-B Composite membrane with acid resistance and alkali resistance as well as preparation method and application thereof 中国石油化工股份有限公司 2023-04-11 CN claimed
CN-114432901-A Composite membrane with acid resistance and alkali resistance as well as preparation method and application thereof 中国石油化工股份有限公司 2022-05-06 CN claimed
CN-118704008-A Copper etching solution for packaging circuit substrate and preparation method and application thereof 浙江奥首材料科技有限公司 2024-09-27 CN disclosed
CN-114249702-B N-aryl- [2,4 '-dithiazole ] -2' -amine compound and preparation and application thereof 沈阳药科大学 2023-09-05 CN disclosed
CN-114432901-B Composite membrane with acid resistance and alkali resistance as well as preparation method and application thereof 中国石油化工股份有限公司 2023-04-11 CN disclosed
US-20220402881-A1 SMALL MOLECULE PROSTAGLADIN TRANSPORT INHIBITORS ALBERT EINSTEIN COLLEGE OF MEDICINE 2022-12-22 US disclosed
CN-115135697-A Process for producing polythioether compound 株式会社大赛璐 2022-09-30 CN disclosed
EP-4054608-A1 SMALL MOLECULE PROSTAGLADIN TRANSPORT INHIBITORS Albert Einstein College of Medicine (US) 2022-09-14 EP disclosed
CN-114432901-A Composite membrane with acid resistance and alkali resistance as well as preparation method and application thereof 中国石油化工股份有限公司 2022-05-06 CN disclosed
CN-114249702-A N-aryl- [2,4 '-bithiazole ] -2' -amine compound and preparation and application thereof 沈阳药科大学 2022-03-29 CN disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20220402881-A1 SMALL MOLECULE PROSTAGLADIN TRANSPORT INHIBITORS PTGER1, PTGIS, PTGIR LMNA 2850/4885HTT 3322/4885ALDH1A1 875/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.