SCHEMBL29641053

SCHEMBL29641053

NCCCC[C@H](NC(=O)[C@@H](N)Cc1ccccc1)C(=O)N[C@@H](CS)C(N)=O

nearest known ligand 0.59

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
MMP2 P08253 1/20 0.53
ERAP2 Q6P179 1/20 0.50
LNPEP Q9UIQ6 1/20 0.50
OPRK1 P41145 1/20 0.50
UTS2R Q9UKP6 1/20 0.49
CTSL P07711 1/20 0.47
GHSR Q92847 2/20 0.47
KISS1R Q969F8 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30099540 0.92 MMP2 (0.56) MMP2ERAP2LNPEPOPRK1CTSL
SCHEMBL30688828 0.91 MMP2 (0.56) MMP2ERAP2LNPEPOPRK1CTSL
SCHEMBL28323436 0.91 MMP2 (0.56) MMP2ERAP2LNPEPOPRK1CTSL
SCHEMBL6431108 0.91 MMP2 (0.56) MMP2ERAP2LNPEPOPRK1CTSL
SCHEMBL29467398 0.90 GNPAT (0.55) MMP2ERAP2LNPEPOPRK1
SCHEMBL29641050 0.89 NPY4R (0.57) KISS1R
SCHEMBL20964460 0.89 MMP2 (0.53) MMP2ERAP2LNPEPOPRK1CTSL
SCHEMBL31602283 0.89 CTSL (0.55) MMP2OPRK1CTSLGHSR
SCHEMBL6466923 0.88 CTSC (0.56) MMP2
SCHEMBL29972888 0.88 MMP2 (0.52) MMP2ERAP2LNPEPOPRK1CTSL

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250161401-A1 METHODS AND COMPOSITIONS FOR THE PREVENTION AND TREATMENT OF DUCHENNE MUSCULAR DYSTROPHY STEALTH BIOTHERAPEUTICS INC. (US) 2025-05-22 US disclosed
US-20240350577-A1 METHODS AND COMPOSITIONS FOR PREVENTING OR TREATING DOMINANT OPTIC ATROPHY STEALTH BIOTHERAPEUTICS INC. (US) 2024-10-24 US disclosed
US-20240108740-A1 THERAPEUTIC COMPOSITIONS INCLUDING SPN10 AND USES THEREOF STEALTH BIOTHERAPEUTICS INC. (US) 2024-04-04 US disclosed
EP-4233887-A1 METHODS FOR THE TREATMENT OF DUCHENNE MUSCULAR DYSTROPHY Stealth BioTherapeutics Inc. (US) 2023-08-30 EP disclosed
US-20230109564-A1 METHODS AND COMPOSITIONS FOR THE PREVENTION AND TREATMENT OF DUCHENNE MUSCULAR DYSTROPHY STEALTH BIOTHERAPEUTICS INC. (US) 2023-04-06 US disclosed
EP-3513800-B1 AROMATIC-CATIONIC PEPTIDE FOR USE IN THE TREATMENT OF ANTIPHOSPHOLIPID SYNDROME UNIV CORNELL (US) 2022-12-07 EP disclosed
EP-4085920-A1 METHODS FOR THE TREATMENT OF DUCHENNE MUSCULAR DYSTROPHY Stealth BioTherapeutics Inc. (US) 2022-11-09 EP disclosed
EP-4000690-A1 COMPOSITIONS AND METHODS FOR THE PREVENTION AND TREATMENT OF MITOCHONDRIAL MYOPATHIES Stealth BioTherapeutics Inc. (US) 2022-05-25 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250161401-A1 METHODS AND COMPOSITIONS FOR THE PREVENTION AND TREATMENT OF DUCHENNE MUSCULAR DYSTROPHY MTPN, UTRN, SMN1; SMN2 MMP2 319/4885ERAP2 312/4885LNPEP 44/4885
US-20230109564-A1 METHODS AND COMPOSITIONS FOR THE PREVENTION AND TREATMENT OF DUCHENNE MUSCULAR DYSTROPHY MTPN, UTRN, SMN1; SMN2 MMP2 319/4885ERAP2 312/4885LNPEP 44/4885
US-20240108740-A1 THERAPEUTIC COMPOSITIONS INCLUDING SPN10 AND USES THEREOF S100A10, SPG11, TMSB10 MMP2 1351/4885ERAP2 1357/4885LNPEP 104/4885
US-20240350577-A1 METHODS AND COMPOSITIONS FOR PREVENTING OR TREATING DOMINANT OPTIC ATROPHY CRYAA, CRYAB, PRPH MMP2 2143/4885ERAP2 633/4885LNPEP 85/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.