Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | DPP4 | P27487 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 2/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | CA12 | O43570 | 1/20 | 0.33 |
| ▸ | CA1 | P00915 | 1/20 | 0.33 |
| ▸ | CA2 | P00918 | 1/20 | 0.33 |
| ▸ | CA3 | P07451 | 1/20 | 0.33 |
| ▸ | CA4 | P22748 | 1/20 | 0.33 |
| ▸ | CA6 | P23280 | 1/20 | 0.33 |
| ▸ | CA5A | P35218 | 1/20 | 0.33 |
| ▸ | CA7 | P43166 | 1/20 | 0.33 |
| ▸ | CA9 | Q16790 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7690653 | 0.77 | SMN1; SMN2 (0.50) | SMN1; SMN2LMNAKMT2AALDH1A1RAB9A | |
| SCHEMBL2962874 | 0.70 | EPHX2 (0.46) | SMN1; SMN2LMNAALDH1A1HSD17B10MAPK1 | |
| SCHEMBL13602153 | 0.70 | SMN1; SMN2 (0.42) | SMN1; SMN2LMNAALDH1A1RAB9A | |
| SCHEMBL321080 | 0.69 | TPMT (0.48) | SMN1; SMN2LMNAKMT2AALDH1A1DPP4 | |
| SCHEMBL111202 | 0.68 | AKR1C4 (0.54) | SMN1; SMN2LMNAKMT2AALDH1A1DPP4 | |
| SCHEMBL8827322 | 0.68 | DPP4 (0.46) | SMN1; SMN2ALDH1A1DPP4KDM4EHSD17B10 | |
| SCHEMBL7689229 | 0.67 | RAB9A (0.46) | SMN1; SMN2LMNAKMT2AALDH1A1RAB9A | |
| SCHEMBL6125794 | 0.67 | TSHR (0.50) | SMN1; SMN2KMT2AALDH1A1RAB9ACA12 | |
| SCHEMBL27996677 | 0.67 | RXRA (0.34) | SMN1; SMN2LMNAALDH1A1DPP4KDM4E | |
| SCHEMBL5878784 | 0.66 | AKR1C4 (0.52) | SMN1; SMN2LMNAKMT2AALDH1A1DPP4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7759388-B2 | Phenylalanine derivatives | AJINOMOTO CO., INC. (JP) | 2010-07-20 | — | — | US | disclosed |
| US-20090048236-A1 | NEW PHENYLALANINE DERIVATIVES | AJINOMOTO CO. INC (JP) | 2009-02-19 | — | — | US | disclosed |
| US-7452905-B2 | Phenylalanine derivatives | AJINOMOTO CO., INC. (JP) | 2008-11-18 | — | — | US | disclosed |
| EP-1323711-B1 | NOVEL PHENYLALANINE DERIVATIVES | AJINOMOTO KK (JP) | 2006-11-15 | — | — | EP | disclosed |
| US-20030220318-A1 | New phenylalanine derivatives | AJINOMOTO CO. INC (JP) | 2003-11-27 | — | — | US | disclosed |
| EP-1323711-A1 | NOVEL PHENYLALANINE DERIVATIVES | Ajinomoto Co., Inc. (JP) | 2003-07-02 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030220318-A1 | New phenylalanine derivatives | VCAM1, PAH, ICAM1 | SMN1; SMN2 2570/4885LMNA 3772/4885KMT2A 2023/4885 |
| US-20090048236-A1 | NEW PHENYLALANINE DERIVATIVES | ITGB4, VCAM1, ITGA4 | SMN1; SMN2 3291/4885LMNA 3883/4885KMT2A 2141/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.