Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MET | P08581 | 2/20 | 0.33 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.33 |
| ▸ | ALK | Q9UM73 | 1/20 | 0.33 |
| ▸ | EGFR | P00533 | 5/20 | 0.33 |
| ▸ | PRKDC | P78527 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 2/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | UBE2N | P61088 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | THRB | P10828 | 1/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.32 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.32 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29646158 | 0.86 | ADORA3 (0.32) | METRXFP1ALKPRKDCTP53 | |
| SCHEMBL29646322 | 0.85 | RXFP1 (0.40) | RXFP1ALKEGFRTHRBTP53 | |
| SCHEMBL29645874 | 0.84 | ADORA3 (0.40) | METALKADORA3ADORA2AADORA1 | |
| SCHEMBL29645782 | 0.84 | MAPT (0.43) | RXFP1ALKPOLBTHRBTP53 | |
| SCHEMBL29645944 | 0.83 | EGFR (0.33) | METEGFRPRKDC | |
| SCHEMBL29645835 | 0.83 | ADORA3 (0.39) | METRXFP1ALKEGFRPOLB | |
| SCHEMBL29645783 | 0.83 | ADORA3 (0.42) | ADORA3 | |
| SCHEMBL29646053 | 0.82 | ADORA3 (0.41) | METALKADORA3ADORA2AADORA1 | |
| SCHEMBL29645664 | 0.82 | ADORA3 (0.40) | METALKADORA3ADORA2AADORA1 | |
| SCHEMBL29645724 | 0.81 | AXL (0.34) | METALKEGFR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114466850-A | [1,2,4] triazolo [1,5-C ] quinazolin-5-amines | 拜耳股份有限公司 | 2022-05-10 | — | — | CN | claimed |
| CN-114466850-A | [1,2,4] triazolo [1,5-C ] quinazolin-5-amines | 拜耳股份有限公司 | 2022-05-10 | — | — | CN | disclosed |