Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM5 | P41594 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | P2RX7 | Q99572 | 2/20 | 0.31 |
| ▸ | USP1 | O94782 | 1/20 | 0.31 |
| ▸ | TTK | P33981 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31149982 | 0.92 | THRB (0.32) | — | |
| SCHEMBL29645597 | 0.88 | TRPA1 (0.34) | GRM5P2RX7 | |
| SCHEMBL29645665 | 0.86 | KDM4E (0.40) | KDM4EALDH1A1 | |
| SCHEMBL29645810 | 0.84 | ADORA3 (0.35) | — | |
| SCHEMBL31150070 | 0.82 | PIM1 (0.33) | — | |
| SCHEMBL29646056 | 0.82 | ALDH1A1 (0.34) | KDM4EALDH1A1P2RX7 | |
| SCHEMBL29645930 | 0.82 | POLB (0.38) | KDM4E | |
| SCHEMBL29645797 | 0.81 | JAK2 (0.32) | P2RX7 | |
| SCHEMBL29646030 | 0.80 | KMT2A (0.35) | KDM4EALDH1A1P2RX7 | |
| SCHEMBL29645825 | 0.80 | TP53 (0.41) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114466850-A | [1,2,4] triazolo [1,5-C ] quinazolin-5-amines | 拜耳股份有限公司 | 2022-05-10 | — | — | CN | claimed |