SCHEMBL29645924

SCHEMBL29645924

CC(C)(C)C(=O)CN1C(=O)[C@H](NC(=O)Nc2cccc(C(=O)O)c2)CN(C2CCCCC2)c2ccccc21

nearest known ligand 0.56

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
CCKBR P32239 17/20 0.54
CCKAR P32238 10/20 0.54

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1556430 1.00 CCKBR (0.54) CCKBRCCKAR
SCHEMBL6177344 1.00 CCKBR (0.54) CCKBRCCKAR
SCHEMBL1556431 1.00 CCKBR (0.54) CCKBRCCKAR
SCHEMBL19949394 1.00 CCKBR (0.54) CCKBRCCKAR
SCHEMBL6177296 1.00 CCKBR (0.54) CCKBRCCKAR
Water SCHEMBL1394819 0.99 CCKBR (0.53) CCKBRCCKAR
Water SCHEMBL29806115 0.99 CCKBR (0.53) CCKBRCCKAR
Water SCHEMBL1394812 0.99 CCKBR (0.53) CCKBRCCKAR
SCHEMBL6177951 0.99 CCKBR (0.53) CCKBRCCKAR
SCHEMBL6177958 0.99 CCKBR (0.53) CCKBRCCKAR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 27 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-122056884-A Methods of treating pancreatic cancer 坎莫森特里克斯公司 2026-05-19 CN claimed
US-20250213523-A1 COMBINATION OF HDAC INHIBITORS AND STATINS FOR USE IN THE TREATMENT OF PANCREATIC CANCER ISTITUTO NAZIONALE TUMORI IRCCS - FONDAZIONE G. PASCALE (IT) 2025-07-03 US claimed
EP-4504165-A1 COMBINATION OF HDAC INHIBITORS AND STATINS FOR USE IN THE TREATMENT OF PANCREATIC CANCER Istituto Nazionale Tumori IRCCS - Fondazione G. Pascale (IT) 2025-02-12 EP claimed
US-11890276-B2 Methods of treating pancreatic cancer CHEMOCENTRYX, INC. (US) 2024-02-06 US claimed
WO-2023194441-A1 COMBINATION OF HDAC INHIBITORS AND STATINS FOR USE IN THE TREATMENT OF PANCREATIC CANCER ISTITUTO NAZIONALE TUMORI IRCCS - FONDAZIONE G. PASCALE (IT) 2023-10-12 WO claimed
CN-122094689-A Combination therapy of diacylglycerol kinase (DGK) alpha inhibitors with other therapies 2026-05-26 CN disclosed
CN-122056884-A Methods of treating pancreatic cancer 坎莫森特里克斯公司 2026-05-19 CN disclosed
EP-4739310-A1 ECTONUCLEOTIDE PYROPHOSPHATASE/PHOSPHODIESTERASE 1 (ENPP1) INHIBITOR COMBINATIONS AND USES THEREOF Insilico Medicine IP Limited (HK) 2026-05-13 EP disclosed
EP-4662319-A2 PERSONALIZED CRISPR PROFILING FOR CANCER Integrate Bioscience LLC (US) 2025-12-17 EP disclosed
EP-4619411-A1 DUAL RECEPTOR TARGETING RADIOLIGANDS AND USES THEREOF Full-Life Technologies HK Limited (HK) 2025-09-24 EP disclosed
US-20250213523-A1 COMBINATION OF HDAC INHIBITORS AND STATINS FOR USE IN THE TREATMENT OF PANCREATIC CANCER ISTITUTO NAZIONALE TUMORI IRCCS - FONDAZIONE G. PASCALE (IT) 2025-07-03 US disclosed
CN-120129690-A Dual receptor targeted radioligands and uses thereof 辐联科技香港有限公司 2025-06-10 CN disclosed
WO-2024083224-A1 DUAL RECEPTOR TARGETING RADIOLIGANDS AND USES THEREOF RELATED APPLICATIONS FULL-LIFE TECHNOLOGIES HK LIMITED (CN) 2024-04-25 WO disclosed
US-11945805-B2 Inhibitors of CXCR2 CHEMOCENTRYX, INC (US) 2024-04-02 US disclosed
EP-3383386-B1 MODULATORS OF CHEMOKINE RECEPTORS CHEMOCENTRYX INC (US) 2024-02-14 EP disclosed
US-11890276-B2 Methods of treating pancreatic cancer CHEMOCENTRYX, INC. (US) 2024-02-06 US disclosed
US-11820759-B2 Modulators of chemokine receptors CHEMOCENTRYX, INC. (US) 2023-11-21 US disclosed
WO-2023194441-A1 COMBINATION OF HDAC INHIBITORS AND STATINS FOR USE IN THE TREATMENT OF PANCREATIC CANCER ISTITUTO NAZIONALE TUMORI IRCCS - FONDAZIONE G. PASCALE (IT) 2023-10-12 WO disclosed
US-20220244263-A1 METHODS FOR TREATING SMALL CELL NEUROENDOCRINE AND RELATED CANCERS THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2022-08-04 US disclosed
US-20220153733-A1 SUBSTITUTED TETRAHYDROPYRANS AS CCR2 MODULATORS CHEMOCENTRYX, INC. 2022-05-19 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11820759-B2 Modulators of chemokine receptors CCR5, CXCR3, CCR2 CCKBR 212/4885CCKAR 137/4885
US-11890276-B2 Methods of treating pancreatic cancer RNASE1, KRAS, PNLIP CCKBR 842/4885CCKAR 1250/4885
US-11945805-B2 Inhibitors of CXCR2 CXCR2, CXCR3, CXCR1 CCKBR 206/4885CCKAR 162/4885
US-20220153733-A1 SUBSTITUTED TETRAHYDROPYRANS AS CCR2 MODULATORS CCR2, CCR1, CCR5 CCKBR 384/4885CCKAR 172/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.