Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RX7 | Q99572 | 5/20 | 0.31 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.30 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29645561 | 0.86 | MAP3K5 (0.34) | P2RX7PIK3CA | |
| SCHEMBL29645592 | 0.81 | CYP1A2 (0.35) | P2RX7LRRK2 | |
| SCHEMBL22979927 | 0.80 | HDAC1 (0.32) | — | |
| SCHEMBL29645573 | 0.80 | PIK3CA (0.31) | P2RX7PIK3CA | |
| SCHEMBL22988221 | 0.80 | LRRK2 (0.32) | LRRK2 | |
| SCHEMBL31150035 | 0.79 | CDK2 (0.35) | — | |
| SCHEMBL29645908 | 0.79 | RIPK1 (0.33) | P2RX7LRRK2PIK3CA | |
| SCHEMBL29646221 | 0.78 | CYP1A2 (0.35) | P2RX7LRRK2 | |
| SCHEMBL29645597 | 0.78 | TRPA1 (0.34) | P2RX7LRRK2 | |
| SCHEMBL29645682 | 0.77 | ADORA3 (0.40) | P2RX7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114466850-A | [1,2,4] triazolo [1,5-C ] quinazolin-5-amines | 拜耳股份有限公司 | 2022-05-10 | — | — | CN | claimed |