SCHEMBL2965154

SCHEMBL2965154

c1ccc(-c2cc(-c3ccccc3)cc(-c3c4ccccc4c(-c4c5ccccc5c(-c5cc(-c6ccccc6)cc(-c6ccccc6)c5)c5ccccc45)c4ccccc34)c2)cc1

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.47
ACHE P22303 2/20 0.41
ESR1 P03372 3/20 0.41
ESR2 Q92731 3/20 0.41
CRHBP P24387 1/20 0.39
CRHR2 Q13324 1/20 0.39
EGFR P00533 1/20 0.38
GPR84 Q9NQS5 1/20 0.37
MAOA P21397 1/20 0.37
KMO O15229 1/20 0.37
MAPT P10636 2/20 0.36
MAPK1 P28482 2/20 0.36
TDP1 Q9NUW8 2/20 0.36
GP6 Q9HCN6 1/20 0.36
HSP90AA1 P07900 1/20 0.36
KDM4E B2RXH2 1/20 0.36
L3MBTL1 Q9Y468 1/20 0.36
CYP1A2 P05177 1/20 0.36
LMNA P02545 1/20 0.36
HTT P42858 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL261400 0.97 ALDH1A1 (0.50) ALDH1A1ACHEESR1ESR2CRHBP
SCHEMBL29373135 0.97 ALDH1A1 (0.50) ALDH1A1ACHEESR1ESR2CRHBP
SCHEMBL23702367 0.95 ALDH1A1 (0.47) ALDH1A1ACHEESR1ESR2CRHBP
SCHEMBL2960612 0.90 ALDH1A1 (0.47) ALDH1A1ACHEESR1ESR2CRHBP
SCHEMBL2085368 0.86 CRHBP (0.43) ALDH1A1ACHEESR1ESR2CRHBP
SCHEMBL30709030 0.86 CYP1A2 (0.46) ALDH1A1ACHEESR1ESR2CYP1A2
SCHEMBL5448953 0.83 ALDH1A1 (0.53) ALDH1A1ACHEESR1ESR2EGFR
SCHEMBL2085806 0.83 ALOX5 (0.52) ALDH1A1ESR1ESR2GPR84MAPT
SCHEMBL261985 0.83 ACHE (0.54) ALDH1A1ACHEESR1ESR2EGFR
Biphenyl SCHEMBL27941416 0.83 ALDH1A1 (0.60) ALDH1A1ACHEESR1ESR2EGFR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20070126347-A1 OLEDS with improved efficiency EASTMAN KODAK COMPANY 2007-06-07 US claimed
US-7183010-B2 Organic light-emitting diode devices with improved operational stability EASTMAN KODAK CORPORATION (US) 2007-02-27 US claimed
US-7175922-B2 Aggregate organic light emitting diode devices with improved operational stability EASTMAN KODAK COMPANY (US) 2007-02-13 US claimed
US-20050106415-A1 Aggregate organic light emitting diode devices with improved operational stability EASTMAN KODAK COMPANY 2005-05-19 US claimed
US-20040076853-A1 Organic light-emitting diode devices with improved operational stability EASTMAN KODAK COMPANY 2004-04-22 US claimed
US-20100025661-A1 Luminescent material and organic electroluminescent device using the same JNC CORPORATION (JP) 2010-02-04 US disclosed
US-7504163-B2 Hole-trapping materials for improved OLED efficiency EASTMAN KODAK COMPANY (US) 2009-03-17 US disclosed
US-20070126347-A1 OLEDS with improved efficiency EASTMAN KODAK COMPANY 2007-06-07 US disclosed
US-7183010-B2 Organic light-emitting diode devices with improved operational stability EASTMAN KODAK CORPORATION (US) 2007-02-27 US disclosed
US-7175922-B2 Aggregate organic light emitting diode devices with improved operational stability EASTMAN KODAK COMPANY (US) 2007-02-13 US disclosed
US-20060141287-A1 OLEDs with improved operational lifetime EASTMAN KODAK COMPANY 2006-06-29 US disclosed
US-20060040131-A1 OLEDs with improved operational lifetime EASTMAN KODAK COMPANY 2006-02-23 US disclosed
US-20060008672-A1 Hole-trapping materials for improved OLED efficiency EASTMAN KODAK COMPANY 2006-01-12 US disclosed
US-20050106415-A1 Aggregate organic light emitting diode devices with improved operational stability EASTMAN KODAK COMPANY 2005-05-19 US disclosed
US-20040076853-A1 Organic light-emitting diode devices with improved operational stability EASTMAN KODAK COMPANY 2004-04-22 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100025661-A1 Luminescent material and organic electroluminescent device using the same TRPV3, TRPC3, HVCN1 ALDH1A1 944/4885ACHE 2211/4885ESR1 1031/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.