Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AXL | P30530 | 1/20 | 1.00 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.58 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.55 |
| ▸ | PRKCI | P41743 | 1/20 | 0.52 |
| ▸ | MET | P08581 | 2/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.50 |
| ▸ | TGFBR1 | P36897 | 3/20 | 0.49 |
| ▸ | PDPK1 | O15530 | 2/20 | 0.49 |
| ▸ | IKBKE | Q14164 | 2/20 | 0.49 |
| ▸ | MAP2K1 | Q02750 | 1/20 | 0.49 |
| ▸ | CCNB2 | O95067 | 1/20 | 0.47 |
| ▸ | CDK1 | P06493 | 1/20 | 0.47 |
| ▸ | CCNB1 | P14635 | 1/20 | 0.47 |
| ▸ | CCNB3 | Q8WWL7 | 1/20 | 0.47 |
| ▸ | CDC7 | O00311 | 3/20 | 0.46 |
| ▸ | CDK2 | P24941 | 2/20 | 0.46 |
| ▸ | MAP4K4 | O95819 | 2/20 | 0.46 |
| ▸ | PIM1 | P11309 | 2/20 | 0.46 |
| ▸ | PRKACA | P17612 | 2/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL410624 | 1.00 | AXL (1.00) | AXLGPR84LRRK2KMT2APRKCI | |
| SCHEMBL5618155 | 0.78 | TGFBR1 (0.71) | AXLGPR84LRRK2KMT2ATGFBR1 | |
| SCHEMBL20846162 | 0.78 | AXL (0.64) | AXLGPR84TGFBR1PDPK1IKBKE | |
| SCHEMBL2111969 | 0.75 | AXL (0.60) | AXLGPR84LRRK2KMT2AMET | |
| SCHEMBL12605500 | 0.75 | AXL (0.60) | AXLGPR84LRRK2KMT2AMET | |
| SCHEMBL5802606 | 0.75 | AXL (0.60) | AXLGPR84LRRK2KMT2AMET | |
| SCHEMBL412615 | 0.75 | AXL (0.60) | AXLGPR84LRRK2KMT2AMET | |
| SCHEMBL31097189 | 0.75 | AXL (0.60) | AXLGPR84LRRK2KMT2APRKCI | |
| SCHEMBL368676 | 0.75 | AXL (0.60) | AXLGPR84LRRK2KMT2AMET | |
| SCHEMBL12188 | 0.75 | AXL (0.60) | AXLGPR84LRRK2KMT2AMET |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20250289817-A1 | SEROTONIN RECEPTOR MODULATORS AND METHODS OF MAKING AND USING THE SAME | KULEON LLC (US) | 2025-09-18 | — | — | US | disclosed |
| CN-119176777-A | Cyclic alpha-hydroxyimide compound and application thereof | 北京英飞智药科技有限公司 | 2024-12-24 | — | — | CN | disclosed |
| CN-117327057-A | Triazine diketone compound as thyroid hormone receptor agonist and synthesis and application thereof | 南京雷正医药科技有限公司 | 2024-01-02 | — | — | CN | disclosed |
| CN-112088157-B | Aryl-bipyridylamine derivatives as phosphatidylinositol phosphokinase inhibitors | 拉文纳制药公司 | 2023-12-26 | — | — | CN | disclosed |
| CN-115160314-B | Heterocyclic aromatic amide compound and preparation method and application thereof | 南方医科大学 | 2023-12-05 | — | — | CN | disclosed |
| CN-116670123-A | Aromatic heterocyclic compound, pharmaceutical composition and application thereof | 湃隆生物科技有限公司（香港） | 2023-08-29 | — | — | CN | disclosed |
| EP-4214199-A1 | CASEIN KINASE 1 DELTA MODULATORS | JANSSEN Pharmaceutica NV (BE) | 2023-07-26 | — | — | EP | disclosed |
| CN-116490503-A | Casein kinase 1 delta modulators | 詹森药业有限公司 | 2023-07-25 | — | — | CN | disclosed |
| CN-109535155-B | Apoptosis-inducing agents for the treatment of cancer and immune and autoimmune diseases | 艾伯维公司 | 2022-07-12 | — | — | CN | disclosed |
| CN-112979647-B | Azaindole derivative containing azaamino acid, preparation and application | 浙江大学 | 2022-05-20 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20250289817-A1 | SEROTONIN RECEPTOR MODULATORS AND METHODS OF MAKING AND USING THE SAME | HTR5A, HTR1A, HTR3A | AXL 3482/4885GPR84 267/4885LRRK2 2102/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.