Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TGM2 | P21980 | 1/20 | 0.52 |
| ▸ | LMNA | P02545 | 2/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
| ▸ | TYR | P14679 | 1/20 | 0.46 |
| ▸ | MMP1 | P03956 | 2/20 | 0.46 |
| ▸ | MMP2 | P08253 | 2/20 | 0.46 |
| ▸ | MMP9 | P14780 | 1/20 | 0.46 |
| ▸ | MMP12 | P39900 | 1/20 | 0.46 |
| ▸ | MME | P08473 | 1/20 | 0.44 |
| ▸ | ECE1 | P42892 | 1/20 | 0.44 |
| ▸ | TPSAB1 | Q15661 | 2/20 | 0.42 |
| ▸ | PLG | P00747 | 1/20 | 0.42 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.42 |
| ▸ | CTSK | P43235 | 2/20 | 0.41 |
| ▸ | CTSL | P07711 | 1/20 | 0.41 |
| ▸ | CTSB | P07858 | 1/20 | 0.41 |
| ▸ | CTSS | P25774 | 1/20 | 0.41 |
| ▸ | CAPN1 | P07384 | 1/20 | 0.41 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.41 |
| ▸ | ATM | Q13315 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL856196 | 0.78 | CTSK (0.61) | LMNAMMEECE1CTSKCTSL | |
| SCHEMBL241564 | 0.78 | CTSK (0.61) | LMNAMMEECE1CTSKCTSL | |
| SCHEMBL241565 | 0.78 | CTSK (0.61) | LMNAMMEECE1CTSKCTSL | |
| Hydrochloric Acid SCHEMBL7400990 | 0.77 | CTSK (0.60) | LMNAMMEECE1CTSKCTSL | |
| Hydrochloric Acid SCHEMBL7400995 | 0.77 | CTSK (0.60) | LMNAMMEECE1CTSKCTSL | |
| SCHEMBL14943200 | 0.76 | TGM2 (0.44) | TGM2SMN1; SMN2MMP1MMP2MMP9 | |
| SCHEMBL29662829 | 0.76 | TGM2 (0.54) | TGM2MMP1MMP2MMP9MMP12 | |
| SCHEMBL7630508 | 0.76 | MMP1 (0.50) | TGM2LMNASMN1; SMN2MMP1MMP2 | |
| SCHEMBL12401181 | 0.75 | TGM2 (0.43) | TGM2SMN1; SMN2MMP1MMP2MMP9 | |
| Trifluoroacetic Acid SCHEMBL2367570 | 0.74 | CAPN1 (0.58) | LMNAMMEECE1CTSKCTSL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114524821-A | Novel spiropyrrolidine derived antiviral drugs | 英安塔制药有限公司 | 2022-05-24 | — | — | CN | disclosed |