SCHEMBL29663833

C[C@H](NC(=O)CNC(=O)[C@H](CCCCN)NC(=O)[C@@H](N)Cc1ccc(O)cc1)C(=O)N[C@@H](CC(N)=O)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCCN)C(=O)O

nearest known ligand 0.58

Predicted protein targets (top 7)

	gene	UniProt	supporting neighbours	confidence
▸	OPRD1	P41143	17/20	0.53

▸	OPRM1	P35372	7/20	0.53

▸	OPRK1	P41145	2/20	0.53

▸	CCKBR	P32239	5/20	0.51

▸	CCKAR	P32238	4/20	0.51

▸	TFPI	P10646	1/20	0.49

▸	OPRL1	P41146	1/20	0.49

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compound	similarity	top predicted	shared targets
SCHEMBL29663842	0.94	TFPI (0.57)	TFPI
SCHEMBL30273402	0.89	OPRD1 (0.53)	OPRD1OPRM1OPRK1CCKBRCCKAR
SCHEMBL29590452	0.89	OPRM1 (0.55)	OPRD1OPRM1OPRK1TFPI
SCHEMBL29376413	0.87	TFPI (0.56)	OPRD1OPRM1OPRK1TFPI
SCHEMBL31243881	0.87	OPRD1 (0.60)	OPRD1OPRM1OPRK1OPRL1
Acetic Acid SCHEMBL29981808	0.86	LNPEP (0.53)	OPRD1OPRM1OPRK1CCKBRCCKAR
SCHEMBL31257066	0.86	OPRD1 (0.61)	OPRD1OPRM1OPRK1
SCHEMBL30271263	0.85	NPY4R (0.61)	OPRD1OPRK1
SCHEMBL31243856	0.85	OPRD1 (0.70)	OPRD1OPRM1OPRK1CCKBRCCKAR
SCHEMBL30900788	0.85	OPRD1 (0.60)	OPRD1OPRM1OPRK1CCKBRCCKAR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

Patent	Title	Assignee	Published	Priority	Filing	Country	Status
US-12214015-B2	Use of c-type natriuretic peptide variants to treat osteoarthritis	BIOMARIN PHARMACEUTICAL INC. (US)	2025-02-04	—	—	US	disclosed
US-20220160836-A1	USE OF C-TYPE NATRIURETIC PEPTIDE VARIANTS TO TREAT OSTEOARTHRITIS	BIOMARIN PHARMACEUTICAL INC.	2022-05-26	—	—	US	disclosed