Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 2/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.42 |
| ▸ | ACLY | P53396 | 5/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | KMO | O15229 | 1/20 | 0.32 |
| ▸ | CNR1 | P21554 | 1/20 | 0.32 |
| ▸ | PLK1 | P53350 | 1/20 | 0.32 |
| ▸ | IDO1 | P14902 | 1/20 | 0.31 |
| ▸ | PSEN1 | P49768 | 2/20 | 0.30 |
| ▸ | PSEN2 | P49810 | 2/20 | 0.30 |
| ▸ | APH1B | Q8WW43 | 2/20 | 0.30 |
| ▸ | NCSTN | Q92542 | 2/20 | 0.30 |
| ▸ | APH1A | Q96BI3 | 2/20 | 0.30 |
| ▸ | PSENEN | Q9NZ42 | 2/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2846115 | 0.79 | PSEN1 (0.46) | CYP3A4CYP2D6ACLYMAPTPSEN1 | |
| SCHEMBL2967390 | 0.75 | CYP3A4 (0.37) | CYP3A4CYP2D6ACLYMAPTALDH1A1 | |
| SCHEMBL10317472 | 0.71 | ACLY (0.35) | ACLYPSEN1PSEN2APH1BNCSTN | |
| SCHEMBL4570713 | 0.62 | ADRB2 (0.34) | MEN1KMT2AIDO1 | |
| SCHEMBL17927652 | 0.62 | KMT2A (0.41) | MAPTPOLBALDH1A1LMNANPSR1 | |
| SCHEMBL1272497 | 0.61 | MAPT (0.50) | MAPTPOLBALDH1A1LMNAMEN1 | |
| SCHEMBL29136975 | 0.58 | LMNA (0.43) | CYP3A4CYP2D6MAPTALDH1A1LMNA | |
| SCHEMBL12253486 | 0.57 | SLC9A1 (0.56) | MAPTPOLBALDH1A1LMNAMEN1 | |
| SCHEMBL3960290 | 0.57 | KMT2A (0.42) | MAPTPOLBALDH1A1LMNANPSR1 | |
| SCHEMBL13797492 | 0.56 | POLB (0.39) | ACLYMAPTPOLBALDH1A1CNR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2125718-B1 | NEW SUBSTITUTED ARYLSULPHONYLGLYCINES, THE PREPARATION THEREOF AND THE USE THEREOF AS PHARMACEUTICAL COMPOSITIONS | BOEHRINGER INGELHEIM INT (DE) | 2010-09-15 | — | — | EP | disclosed |