Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPA1 | O75762 | 1/20 | 0.45 |
| ▸ | CYP11B2 | P19099 | 4/20 | 0.42 |
| ▸ | CYP11B1 | P15538 | 3/20 | 0.42 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | PNMT | P11086 | 1/20 | 0.33 |
| ▸ | IP6K1 | Q92551 | 1/20 | 0.33 |
| ▸ | IP6K3 | Q96PC2 | 1/20 | 0.33 |
| ▸ | CA1 | P00915 | 1/20 | 0.33 |
| ▸ | CA2 | P00918 | 1/20 | 0.33 |
| ▸ | CA4 | P22748 | 1/20 | 0.33 |
| ▸ | CA6 | P23280 | 1/20 | 0.33 |
| ▸ | DCLK1 | O15075 | 1/20 | 0.33 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.33 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.33 |
| ▸ | CHEK2 | O96017 | 1/20 | 0.33 |
| ▸ | CSF1R | P07333 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2964136 | 0.86 | CYP11B1 (0.42) | TRPA1CYP11B2CYP11B1CYP19A1ALDH1A1 | |
| Hydrochloric Acid SCHEMBL28814933 | 0.79 | CYP11B2 (0.46) | CYP11B2CYP11B1CYP19A1ALDH1A1IP6K1 | |
| SCHEMBL16516818 | 0.78 | CYP11B2 (0.53) | TRPA1CYP11B2CYP11B1CYP19A1ALDH1A1 | |
| SCHEMBL31608568 | 0.77 | CYP11B2 (0.65) | TRPA1CYP11B2CYP11B1CYP19A1IP6K1 | |
| SCHEMBL319265 | 0.77 | CYP11B2 (0.65) | TRPA1CYP11B2CYP11B1CYP19A1IP6K1 | |
| SCHEMBL28814932 | 0.76 | CYP11B1 (0.41) | CYP11B2CYP11B1CYP19A1ALDH1A1IP6K1 | |
| SCHEMBL31666281 | 0.75 | CYP11B2 (0.62) | TRPA1CYP11B2CYP11B1CYP19A1IP6K1 | |
| SCHEMBL19432718 | 0.75 | MMP3 (0.48) | CYP11B2CYP11B1CYP19A1TDP2 | |
| SCHEMBL2958353 | 0.74 | TRPA1 (0.39) | TRPA1ALDH1A1TDP1L3MBTL1CA1 | |
| SCHEMBL2958175 | 0.73 | PIK3R1 (0.42) | TRPA1ALDH1A1TDP1L3MBTL1CSNK1D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9905777-B2 | Compound and organic electroluminescence device comprising same | DOOSAN CORPORATION (KR) | 2018-02-27 | — | — | US | disclosed |
| US-9837618-B2 | Compound and organic electroluminescence device including thesame | DOOSAN CORPORATION (KR) | 2017-12-05 | — | — | US | disclosed |
| US-20150246902-A1 | SUBSTITUED BENZOFURAN COMPOUNDS AND METHODS OF USE THEREOF FOR THE TREATMENT OF VIRAL DISEASES | MERCK SHARP & DOHME CORP. (US) | 2015-09-03 | — | — | US | disclosed |
| US-20150236272-A1 | NOVEL COMPOUND AND ORGANIC ELECTROLUMINESCENCE DEVICE INCLUDING THESAME | DOOSAN CORPORATION (KR) | 2015-08-20 | — | — | US | disclosed |
| US-20150236271-A1 | NOVEL COMPOUND AND ORGANIC ELECTROLUMINESCENCE DEVICE COMPRISING SAME | DOOSAN CORPORATION (KR) | 2015-08-20 | — | — | US | disclosed |
| US-7763562-B2 | Heteroatom bridged metallocene compounds for olefin polymerization | EXXONMOBIL CHEMICAL PATENTS INC. (US) | 2010-07-27 | — | — | US | disclosed |
| US-20070135597-A1 | Heteroatom bridged metallocene compounds for olefin polymerization | EXXONMOBIL CHEMICAL PATENTS INC. | 2007-06-14 | — | — | US | disclosed |
| WO-2006065809-A2 | HETEROATOM BRIDGED METALLOCENE COMPOUNDS FOR OLEFIN POLYMERIZATION | EXXONMOBIL CHEMICAL PATENTS INC. (US) | 2006-06-22 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150246902-A1 | SUBSTITUED BENZOFURAN COMPOUNDS AND METHODS OF USE THEREOF FOR THE TREATMENT OF VIRAL DISEASES | EIF5B, EIF2AK2, HCCS | TRPA1 3845/4885CYP11B2 371/4885CYP11B1 298/4885 |
| US-20070135597-A1 | Heteroatom bridged metallocene compounds for olefin polymerization | AP2M1, AP1M1, PYM1 | TRPA1 438/4885CYP11B2 3583/4885CYP11B1 3696/4885 |
| US-20150236272-A1 | NOVEL COMPOUND AND ORGANIC ELECTROLUMINESCENCE DEVICE INCLUDING THESAME | INMT, IDO1, IDO2 | TRPA1 14/4885CYP11B2 653/4885CYP11B1 774/4885 |
| US-20150236271-A1 | NOVEL COMPOUND AND ORGANIC ELECTROLUMINESCENCE DEVICE COMPRISING SAME | OR10J3, VDAC1, VDAC2 | TRPA1 11/4885CYP11B2 2636/4885CYP11B1 2988/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.