SCHEMBL29679057

SCHEMBL29679057

NCC1CCC(C(=O)N[C@@H](Cc2ccc3ccccc3c2)C(=O)NCCCC[C@H](NC(=O)N[C@@H](CCC(=O)O)C(=O)O)C(=O)O)CC1

nearest known ligand 0.76

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
▸ FOLH1 Q04609 13/20 0.76
▸ PLG P00747 7/20 0.62
▸ PRSS1 P07477 7/20 0.62
▸ PRSS2 P07478 7/20 0.62
▸ PRSS3 P35030 7/20 0.62
▸ PLAU P00749 2/20 0.53

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23553003 1.00 FOLH1 (0.76) FOLH1PLGPRSS1PRSS2PRSS3
SCHEMBL29679477 1.00 FOLH1 (0.76) FOLH1PLGPRSS1PRSS2PRSS3
SCHEMBL26090338 1.00 FOLH1 (0.76) FOLH1PLGPRSS1PRSS2PRSS3
SCHEMBL28659047 1.00 FOLH1 (0.76) FOLH1PLGPRSS1PRSS2PRSS3
SCHEMBL22883093 0.93 FOLH1 (0.75) FOLH1PLGPRSS1PRSS2PRSS3
SCHEMBL19296397 0.92 FOLH1 (0.76) FOLH1PLGPRSS1PRSS2PRSS3
SCHEMBL27303660 0.92 FOLH1 (0.73) FOLH1PLGPRSS1PRSS2PRSS3
SCHEMBL26178698 0.92 FOLH1 (0.78) FOLH1PLGPRSS1PRSS2PRSS3
SCHEMBL26001462 0.92 FOLH1 (0.78) FOLH1PLGPRSS1PRSS2PRSS3
SCHEMBL22883091 0.91 FOLH1 (0.72) FOLH1PLGPRSS1PRSS2PRSS3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250332296-A1 ZWITTERIONIC METAL CHELATORS CURADEL SURGICAL INNOVATIONS, INC. (US) 2025-10-30 — — US disclosed
US-20250332295-A1 ZWITTERIONIC METAL CHELATORS CURADEL SURGICAL INNOVATIONS, INC. (US) 2025-10-30 — — US disclosed
US-20250325713-A1 DISEASE-TARGETED IMAGING AGENTS CURADEL SURGICAL INNOVATIONS INC (US) 2025-10-23 — — US disclosed
US-20250325712-A1 TARGETING LIGANDS FOR DISEASE-TARGETED IMAGING AGENTS AND METHODS OF USE THEREFOR CURADEL SURGICAL INNOVATIONS INC (US) 2025-10-23 — — US disclosed
US-12440585-B2 Zwitterionic metal chelators CURADEL SURGICAL INNOVATIONS, INC. (US) 2025-10-14 — — US disclosed
WO-2025059116-A1 COMBINATIONS OF IMAGING AGENT CONJUGATES AND APPLICATION THEREOF CURADEL SURGICAL INNOVATIONS, INC. (US) 2025-03-20 — — WO disclosed
WO-2025059124-A1 N-OXIDE BASED ZWITTERIONIC NEAR INFRARED FLUOROPHORE IMAGING AGENTS AND METHODS OF USE THEREFOR CURADEL SURGICAL INNOVATIONS, INC. (US) 2025-03-20 — — WO disclosed
US-20250090697-A1 ZWITTERIONIC METAL CHELATORS CURADEL SURGICAL INNOVATIONS, INC. 2025-03-20 — — US disclosed
WO-2025059097-A1 DISEASE-TARGETED IMAGING AGENTS CURADEL SURGICAL INNOVATIONS, INC. (US) 2025-03-20 — — WO disclosed
WO-2025059044-A1 TARGETING LIGANDS FOR DISEASE-TARGETED IMAGING AGENTS AND METHODS OF USE THEREFOR CURADEL SURGICAL INNOVATIONS, INC. (US) 2025-03-20 — — WO disclosed
US-20250082795-A1 COMBINATIONS OF IMAGING AGENT CONJUGATES AND APPLICATION THEREOF CURADEL SURGICAL INNOVATIONS, INC. 2025-03-13 — — US disclosed
US-20250082792-A1 ZWITTERIONIC METAL CHELATORS CURADEL SURGICAL INNOVATIONS, INC. 2025-03-13 — — US disclosed
WO-2024222575-A1 MACROCYCLIC CHELATING AGENT CAPABLE OF SITE-SPECIFIC MODIFICATION, RADIONUCLIDE PROBE, AND USE THEREOF 中国科学院上海药物研究所 2024-10-31 — — WO disclosed
EP-4003959-A1 TARGETED RADIOPHARMACEUTICALS FOR THE DIAGNOSIS AND TREATMENT OF PROSTATE CANCER Bayer AS (NO) 2022-06-01 — — EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (8 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12440585-B2 Zwitterionic metal chelators SLC39A14, SLC7A1, SLC39A11 FOLH1 66/4885PLG 1194/4885PRSS1 2771/4885
US-20250332295-A1 ZWITTERIONIC METAL CHELATORS SLC39A14, SLC7A1, SLC39A11 FOLH1 66/4885PLG 1194/4885PRSS1 2771/4885
US-20250325712-A1 TARGETING LIGANDS FOR DISEASE-TARGETED IMAGING AGENTS AND METHODS OF USE THEREFOR LGALS1, LGALS8, CD74 FOLH1 20/4885PLG 514/4885PRSS1 1685/4885
US-20250325713-A1 DISEASE-TARGETED IMAGING AGENTS FAP, PROKR1, GRPR FOLH1 52/4885PLG 1335/4885PRSS1 271/4885
US-20250082795-A1 COMBINATIONS OF IMAGING AGENT CONJUGATES AND APPLICATION THEREOF FAM83E, FAM83A, BMPR1A FOLH1 293/4885PLG 439/4885PRSS1 907/4885
US-20250082792-A1 ZWITTERIONIC METAL CHELATORS SLC39A14, SLC7A1, SLC39A11 FOLH1 66/4885PLG 1194/4885PRSS1 2771/4885
US-20250090697-A1 ZWITTERIONIC METAL CHELATORS SLC39A14, SLC7A1, SLC39A11 FOLH1 66/4885PLG 1194/4885PRSS1 2771/4885
US-20250332296-A1 ZWITTERIONIC METAL CHELATORS SLC39A14, SLC7A1, SLC39A11 FOLH1 66/4885PLG 1194/4885PRSS1 2771/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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