Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 4/20 | 0.53 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.37 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.37 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | APEX1 | P27695 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | THRB | P10828 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.34 |
| ▸ | HPGD | P15428 | 2/20 | 0.34 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.34 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | PKM | P14618 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL296808 | 0.89 | TSHR (0.55) | TSHRPOLBAPEX1HTTTDP1 | |
| SCHEMBL713937 | 0.86 | TSHR (0.60) | TSHRPOLBAPEX1HTTTDP1 | |
| Acrylic Acid SCHEMBL28196913 | 0.82 | TSHR (0.47) | TSHRPOLBAPEX1HTTTDP1 | |
| SCHEMBL714605 | 0.81 | TSHR (0.58) | TSHRPOLBAPEX1HTTTDP1 | |
| SCHEMBL16232460 | 0.79 | TSHR (0.51) | TSHRPOLBAPEX1HTTTDP1 | |
| SCHEMBL3180135 | 0.78 | TSHR (0.53) | TSHRPOLBAPEX1HTTTDP1 | |
| SCHEMBL28516593 | 0.77 | ALDH1A1 (0.46) | TSHRALDH1A1HPGDCYP1A2CYP2D6 | |
| SCHEMBL5270061 | 0.76 | TSHR (0.47) | TSHRHTTTDP1ALDH1A1HPGD | |
| SCHEMBL1685754 | 0.75 | TSHR (0.50) | TSHRPOLBAPEX1HTTTDP1 | |
| SCHEMBL22566613 | 0.75 | TSHR (0.46) | TSHRPOLBAPEX1HTTTDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 21 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2657304-B1 | AZO DYE, OCULAR LENS MATERIAL, METHOD FOR PRODUCING OCULAR LENS MATERIAL, AND OCULAR LENS | MENICON CO LTD (JP) | 2022-12-07 | — | — | EP | disclosed |
| US-9017716-B2 | Ophthalmic lens | MENICON CO., LTD. (JP) | 2015-04-28 | — | — | US | disclosed |
| EP-2657304-A1 | AZO DYE, OCULAR LENS MATERIAL, METHOD FOR PRODUCING OCULAR LENS MATERIAL, AND OCULAR LENS | Menicon Co., Ltd. (JP) | 2013-10-30 | — | — | EP | disclosed |
| EP-2180366-B1 | SILICONE-CONTAINING OCULAR LENS MATERIAL WITH HIGH SAFETY AND PREPARING METHOD THEREOF | MENICON CO LTD (JP) | 2013-09-25 | — | — | EP | disclosed |
| US-20130202551-A1 | IONIC COMPOUND, COMPOSITION, CURED MATERIAL, HYDROGEL AND OPHTHALMIC LENS | MENICON CO., LTD. (JP) | 2013-08-08 | — | — | US | disclosed |
| EP-2581394-A1 | IONIC COMPOUND, COMPOSITION, CURED PRODUCT, HYDROGEL, AND OCULAR LENS | Menicon Co., Ltd. (JP) | 2013-04-17 | — | — | EP | disclosed |
| EP-2514791-A1 | ANTHRAQUINONE PIGMENT, OCULAR LENS MATERIAL USING SAME, OCULAR LENS MATERIAL MANUFACTURING METHOD, AND OCULAR LENS | Menicon Co., Ltd. (JP) | 2012-10-24 | — | — | EP | disclosed |
| US-20120148519-A1 | OPHTHALMIC LENS | MENICON CO., LTD. (JP) | 2012-06-14 | — | — | US | disclosed |
| EP-2453293-A1 | OPHTHALMIC LENS | Menicon Co., Ltd. (JP) | 2012-05-16 | — | — | EP | disclosed |
| US-8124668-B2 | Silicone-containing ocular lens material with high safety and preparing method thereof | MENICON CO., LTD. (JP) | 2012-02-28 | — | — | US | disclosed |
| US-20060142410-A1 | Silicone-containing ocular lens material with high safety and preparing method thereof | MENICON CO., LTD. (JP) | 2006-06-29 | — | — | US | disclosed |
| US-7037954-B2 | Ocular lens material | MENICON CO., LTD. (JP) | 2006-05-02 | — | — | US | disclosed |
| EP-1582910-A1 | HIGHLY SAFE SILICONE-CONTAINING MATERIAL FOR OCULAR LENS AND PROCESS FOR PRODUCING THE SAME | MENICON CO., LTD. (JP) | 2005-10-05 | — | — | EP | disclosed |
| EP-1197782-B1 | MATERIAL FOR OCULAR LENS | MENICON CO LTD (JP) | 2004-06-02 | — | — | EP | disclosed |
| US-20040039077-A1 | Ocular lens material | MENICON CO., LTD. | 2004-02-26 | — | — | US | disclosed |
| US-6638991-B2 | Lens material comprising a copolymer derived from a polysiloxane endcapped with acrylated urethane groups, a silicon-containing alkyl methacrylate, a hydrophilic monomer, and a crosslinking monomer; oxygen permeability, strength | MENICON CO., LTD. (JP) | 2003-10-28 | — | — | US | disclosed |
| US-20020198280-A1 | Material for ocular lens | MENICON CO., LTD. (JP) | 2002-12-26 | — | — | US | disclosed |
| EP-1197782-A1 | MATERIAL FOR OCULAR LENS | MENICON CO., LTD. (JP) | 2002-04-17 | — | — | EP | disclosed |
| US-5587445-A | Highly oxygen-permeable heat-resistant material | MENICON CO., LTD. (JP) | 1996-12-24 | — | — | US | disclosed |
| US-5556929-A | FROM UNSATURATED DIESTER WITH URETHANE AND FLUORINE GROUPS AND ACRYLATED SILOXANE, CONTACT LENSES | MENICON CO., LTD. (JP) | 1996-09-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120148519-A1 | OPHTHALMIC LENS | AQP4, CRYAA, UACA | TSHR 1228/4885HDAC4 154/4885HDAC2 668/4885 |
| US-20130202551-A1 | IONIC COMPOUND, COMPOSITION, CURED MATERIAL, HYDROGEL AND OPHTHALMIC LENS | CRYZ, CRYAA, VIL1 | TSHR 4720/4885HDAC4 1731/4885HDAC2 2248/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.