Oleandomycin

Oleandomycin

SCHEMBL29684259

CO[C@H]1C[C@H](O[C@H]2[C@@H](C)[C@@H](O[C@@H]3O[C@@H](C)C[C@H](N(C)C)[C@H]3O)[C@H](C)C[C@@]3(CO3)C(=O)[C@H](C)[C@H](O)[C@@H](C)[C@H](C)OC(=O)[C@H]2C)O[C@@H](C)[C@@H]1O

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Full drug profile on Sugi Atlas →

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
CYP3A4 P08684 12/20 1.00
LMNA P02545 3/20 1.00
ABCB1 P08183 3/20 0.71
USP2 O75604 2/20 0.71
MLNR O43193 4/20 0.45
KCNH2 Q12809 5/20 0.44
AR P10275 1/20 0.44
MAPK1 P28482 1/20 0.44
SLCO1B3 Q9NPD5 1/20 0.44
SLCO1B1 Q9Y6L6 1/20 0.44
TSHR P16473 2/20 0.43
TDP1 Q9NUW8 1/20 0.43
ALB P02768 1/20 0.43
CNR1 P21554 1/20 0.43
HTR2A P28223 1/20 0.43
AOX1 Q06278 1/20 0.43
CYP1B1 Q16678 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Oleandomycin SCHEMBL3717 1.00 CYP3A4 (1.00) CYP3A4LMNAABCB1USP2MLNR
Oleandomycin SCHEMBL10028439 1.00 CYP3A4 (1.00) CYP3A4LMNAABCB1USP2MLNR
Oleandomycin SCHEMBL3716 1.00 CYP3A4 (1.00) CYP3A4LMNAABCB1USP2MLNR
Oleandomycin SCHEMBL9807053 0.99 CYP3A4 (0.99) CYP3A4LMNAABCB1USP2MLNR
Oleandomycin SCHEMBL950913 0.98 CYP3A4 (0.96) CYP3A4LMNAABCB1USP2MLNR
Oleandomycin SCHEMBL5033021 0.97 CYP3A4 (1.00) CYP3A4LMNAABCB1USP2MLNR
Oleandomycin SCHEMBL285338 0.97 CYP3A4 (1.00) CYP3A4LMNAABCB1USP2MLNR
SCHEMBL11029029 0.92 CYP3A4 (0.85) CYP3A4LMNAABCB1USP2MLNR
Diproleandomycin SCHEMBL2109038 0.87 CYP3A4 (0.78) CYP3A4LMNAABCB1USP2MLNR
SCHEMBL5551907 0.86 CYP3A4 (0.74) CYP3A4LMNAABCB1USP2MLNR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 22 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118908197-A Graphene preparation process of medium-high voltage power cable 浙江物产中大线缆有限公司 2024-11-08 CN claimed
US-20260083853-A1 CD70 ANTIBODY DRUG CONJUGATES AND METHODS OF USING THE SAME GENMAB AS (DK) 2026-03-26 US disclosed
EP-4608451-A1 CD70 ANTIBODY DRUG CONJUGATES AND METHODS OF USING THE SAME Genmab A/S (DK) 2025-09-03 EP disclosed
CN-119688569-A High flux electron special gas corrosion simulation system 东北大学 2025-03-25 CN disclosed
CN-119049958-A Method for preparing semiconductor structure and semiconductor structure 上海积塔半导体有限公司 2024-11-29 CN disclosed
CN-118908197-A Graphene preparation process of medium-high voltage power cable 浙江物产中大线缆有限公司 2024-11-08 CN disclosed
WO-2024169751-A1 SEMICONDUCTOR DEVICE, MANUFACTURING METHOD THEREFOR, CHIP AND ELECTRONIC APPARATUS 华为技术有限公司 2024-08-22 WO disclosed
CN-118522761-A Semiconductor device, manufacturing method thereof, chip and electronic equipment 华为技术有限公司 2024-08-20 CN disclosed
CN-110086295-B Cooling structure and method of magnetic suspension refrigeration compressor 天津飞旋科技股份有限公司 2024-07-23 CN disclosed
CN-118264267-A Radio frequency front-end module, electronic equipment, control method and device thereof OPPO广东移动通信有限公司 2024-06-28 CN disclosed
WO-2024092067-A1 CD70 ANTIBODY DRUG CONJUGATES AND METHODS OF USING THE SAME PROFOUNDBIO US CO. (US) 2024-05-02 WO disclosed
CN-117143208-A Hypersensitive polypeptide capable of being used for preventing and controlling taro epidemic disease and application thereof 福州市承肽农业生物科技有限公司 2023-12-01 CN disclosed
CN-106772296-B Meteorological radar echo intensity calibration device and method 南京大学 2023-11-07 CN disclosed
US-11708358-B2 Fungicidal oxadiazoles FMC CORPORATION (US) 2023-07-25 US disclosed
WO-2023041187-A1 SYSTEM FOR TESTING FUNCTIONALITIES OF A COMPUTER APPLICATION CIRCLE INTERNET SERVICES INC. (US) 2023-03-23 WO disclosed
CN-114785290-B Envelope tracking power modulator, chip and radio frequency amplification system 绍兴圆方半导体有限公司 2022-09-09 CN disclosed
CN-112979770-B Protein A mutant, fusion protein and application 广东菲鹏生物有限公司 2022-07-26 CN disclosed
CN-114785290-A Envelope tracking power modulator, chip and radio frequency amplification system 绍兴圆方半导体有限公司 2022-07-22 CN disclosed
CN-114763346-A Compound for inducing chondrogenesis and application thereof 华东师范大学 2022-07-19 CN disclosed
US-11384408-B2 Surface treatment method of metallic materials XI'AN JIAOTONG UNIVERSITY (CN) 2022-07-12 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260083853-A1 CD70 ANTIBODY DRUG CONJUGATES AND METHODS OF USING THE SAME CD74, HACD3, FCGR2A CYP3A4 3666/4885LMNA 2777/4885ABCB1 1145/4885
US-11708358-B2 Fungicidal oxadiazoles OXA1L, NOX1, TH CYP3A4 58/4885LMNA 3846/4885ABCB1 189/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.