SCHEMBL2968461

SCHEMBL2968461

CC(=O)c1ccc(OC2CCCCO2)cc1O

nearest known ligand 0.51

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.50
CYP3A4 P08684 1/20 0.50
HPGD P15428 1/20 0.50
MAPK1 P28482 1/20 0.50
MAOB P27338 16/20 0.45
MAOA P21397 4/20 0.42
PPARD Q03181 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30065877 1.00 ALDH1A1 (0.50) ALDH1A1CYP3A4HPGDMAPK1MAOB
SCHEMBL4119366 0.90 MAOB (0.40) ALDH1A1CYP3A4HPGDMAPK1MAOB
SCHEMBL30113210 0.88 MEN1 (0.46) ALDH1A1CYP3A4MAOB
SCHEMBL18796518 0.88 MEN1 (0.46) ALDH1A1CYP3A4MAOB
SCHEMBL30113113 0.87 CA12 (0.49) ALDH1A1CYP3A4HPGDMAPK1
SCHEMBL18796365 0.87 CA12 (0.49) ALDH1A1CYP3A4HPGDMAPK1
SCHEMBL5618972 0.87 MEN1 (0.43) ALDH1A1HPGD
SCHEMBL3685410 0.86 MAOB (0.43) MAOBMAOA
SCHEMBL27445640 0.86 HSD11B1 (0.41) ALDH1A1CYP3A4HPGDMAPK1
SCHEMBL6908438 0.84 GAA (0.41) CYP3A4MAPK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250042911-A1 NOVEL BENZOPYRAN DERIVATIVE AND USE THEREOF SPARK BIOPHARMA, INC. (KR) 2025-02-06 US disclosed
EP-4365175-A1 NOVEL BENZOPYRAN DERIVATIVE AND USE THEREOF Spark Biopharma, Inc. (KR) 2024-05-08 EP disclosed
CN-117897386-A Benzopyran derivatives and uses thereof 斯帕克生物制药有限公司 2024-04-16 CN disclosed
US-20230125487-A1 COMPOSITION FOR TREATING OR PREVENTING INFLAMMATORY BOWEL DISEASE FUGENBIO CO., LTD. (KR) 2023-04-27 US disclosed
US-20160130394-A1 ISOFLAVONE-BASED POLYMER, LENS AND CAMERA MODULE USING THE SAME SAMSUNG ELECTRO-MECHANICS CO., LTD. (KR) 2016-05-12 US disclosed
US-20160130394-A1 ISOFLAVONE-BASED POLYMER, LENS AND CAMERA MODULE USING THE SAME SAMSUNG ELECTRO-MECHANICS CO., LTD. (KR) 2016-05-12 US disclosed
EP-2253226-B1 Use of hydroxyflavone derivatives for modifying taste LEIBNIZ INST FÜR PFLANZENBIOCHEMIE IPB (DE) 2015-07-15 EP disclosed
EP-2253226-A1 Use of hydroxyflavone derivatives for modifying taste Leibniz-Institut für Pflanzenbiochemie (IPB) (DE) 2010-11-24 EP disclosed
US-20100292175-A1 USE OF HYDROXYFLAVAN DERIVATIVES FOR TASTE MODIFICATION Leibniz-Institut fur Pflanzenbiochemie (DE) 2010-11-18 US disclosed
WO-2009026658-A1 PPAR AGONISTS THE UNIVERSITY OF SYDNEY (AU) 2009-03-05 WO disclosed
WO-2009026657-A1 FLAVONOID PPAR AGONISTS THE UNIVERSITY OF SYDNEY (AU) 2009-03-05 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230125487-A1 COMPOSITION FOR TREATING OR PREVENTING INFLAMMATORY BOWEL DISEASE SLC10A2, SI, FABP2 ALDH1A1 2671/4885CYP3A4 4320/4885HPGD 727/4885
US-20250042911-A1 NOVEL BENZOPYRAN DERIVATIVE AND USE THEREOF MYD88, MYADM, CD14 ALDH1A1 2146/4885CYP3A4 428/4885HPGD 229/4885
US-20100292175-A1 USE OF HYDROXYFLAVAN DERIVATIVES FOR TASTE MODIFICATION TAS2R50, TAS2R60, TAS2R30 ALDH1A1 450/4885CYP3A4 1777/4885HPGD 537/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.