Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATF4 | P18848 | 4/20 | 0.35 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22362680 | 0.79 | ATF4 (0.44) | ATF4HDAC4 | |
| SCHEMBL21220171 | 0.64 | MEN1 (0.40) | HDAC4 | |
| SCHEMBL22614325 | 0.63 | POLB (0.43) | — | |
| SCHEMBL29686842 | 0.63 | RAB9A (0.46) | — | |
| SCHEMBL22613807 | 0.63 | CDH1 (0.48) | — | |
| SCHEMBL25386467 | 0.63 | PKM (0.39) | ATF4 | |
| SCHEMBL15258671 | 0.63 | HDAC3 (0.47) | ATF4HDAC4 | |
| SCHEMBL25384051 | 0.62 | NPC1 (0.34) | ATF4 | |
| SCHEMBL16161986 | 0.60 | HDAC4 (0.47) | HDAC4 | |
| SCHEMBL23358860 | 0.60 | ERCC5 (0.45) | ATF4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4247811-A1 | BICYCLO[1.1.1]PENTANE COMPOUNDS FOR THE TREATMENT AND PROPHYLAXIS OF HEPATITIS B VIRUS INFECTION | F. Hoffmann-La Roche AG (CH) | 2023-09-27 | — | — | EP | disclosed |
| WO-2022106375-A1 | BICYCLO[1.1.1]PENTANE COMPOUNDS FOR THE TREATMENT AND PROPHYLAXIS OF HEPATITIS B VIRUS INFECTION | F. HOFFMANN-LA ROCHE AG (CH) | 2022-05-27 | — | — | WO | disclosed |