SCHEMBL29693296

SCHEMBL29693296

CC1(C)CCC(Cc2ccc(Cl)cc2)C1

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.43
TRPA1 O75762 1/20 0.40
CCR5 P51681 1/20 0.40
FPR2 P25090 3/20 0.36
PROKR1 Q8TCW9 3/20 0.36
CXCR3 P49682 1/20 0.36
P2RX7 Q99572 1/20 0.36
GMNN O75496 1/20 0.35
TP53 P04637 1/20 0.35
CYP3A4 P08684 1/20 0.35
ALOX15 P16050 1/20 0.35
TSHR P16473 1/20 0.35
NFKB1 P19838 1/20 0.35
THPO P40225 1/20 0.35
MTOR P42345 1/20 0.35
BLM P54132 1/20 0.35
GRIN1 Q05586 1/20 0.35
GRIN2B Q13224 1/20 0.35
NPSR1 Q6W5P4 1/20 0.35
RPS6KB1 P23443 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1119467 0.75 ALDH1A1 (0.59) ALDH1A1FPR2PROKR1GMNNTP53
SCHEMBL4665533 0.74 TRPA1 (0.38) ALDH1A1TRPA1CCR5P2RX7
SCHEMBL6784500 0.71 ALDH1A1 (0.45) ALDH1A1CYP3A4NPSR1POLB
SCHEMBL1120548 0.71 AOC3 (0.31)
SCHEMBL4665489 0.71 TRPA1 (0.38) TRPA1CCR5POLB
SCHEMBL13504117 0.71 ALDH1A1 (0.51) ALDH1A1FPR2PROKR1GMNNTP53
SCHEMBL25838949 0.70 ALDH1A1 (0.54) ALDH1A1CYP3A4POLB
SCHEMBL5599137 0.68 CCR5 (0.31) CCR5
SCHEMBL2056158 0.68 ALDH1A1 (0.61) ALDH1A1FPR2PROKR1GMNNTP53
SCHEMBL9056250 0.68 MAOB (0.44) ALDH1A1TRPA1P2RX7TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-114773279-B Novel synthesis method of metconazole 浙江工业大学 2023-12-05 CN claimed
CN-114773279-A Novel synthesis method of metconazole 浙江工业大学 2022-07-22 CN claimed
CN-119118933-A Green preparation method of metconazole 江苏剑牌农化科技有限公司 2024-12-13 CN disclosed
CN-118084640-A Preparation method of metconazole key intermediate 5- (4-chlorophenyl) methyl-2, 2-dimethylcyclopentanone 临海市建新化工有限公司 2024-05-28 CN disclosed
CN-114773279-B Novel synthesis method of metconazole 浙江工业大学 2023-12-05 CN disclosed
CN-114773279-B Novel synthesis method of metconazole 浙江工业大学 2023-12-05 CN disclosed
CN-114773279-A Novel synthesis method of metconazole 浙江工业大学 2022-07-22 CN disclosed
CN-114773279-A Novel synthesis method of metconazole 浙江工业大学 2022-07-22 CN disclosed