SCHEMBL29695595

SCHEMBL29695595

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nearest known ligand 0.43

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
▸ PTPN1 P18031 3/20 0.43
▸ GLO1 Q04760 1/20 0.42
▸ BACE1 P56817 5/20 0.41
▸ OPRD1 P41143 5/20 0.41
▸ CCKAR P32238 3/20 0.41
▸ CCKBR P32239 3/20 0.41
▸ EGFR P00533 1/20 0.41
▸ GNPAT O15228 1/20 0.40
▸ CTSD P07339 1/20 0.39
▸ PTGS1 P23219 1/20 0.39
▸ GSTK1 Q9Y2Q3 1/20 0.39
▸ OPRM1 P35372 1/20 0.39
▸ OPRK1 P41145 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30974122 0.95 GLO1 (0.43) PTPN1GLO1BACE1OPRD1EGFR
SCHEMBL29695472 0.91 BACE1 (0.46) BACE1OPRD1CTSD
SCHEMBL30873780 0.90 GNPAT (0.47) PTPN1BACE1GNPATCTSD
SCHEMBL30099711 0.89 GLO1 (0.42) GLO1GNPATPTGS1GSTK1
SCHEMBL29591098 0.89 ENPEP (0.46) PTPN1BACE1GNPATCTSD
SCHEMBL29772105 0.88 BACE1 (0.42) BACE1OPRD1EGFRCTSDOPRM1
SCHEMBL29630690 0.88 FOLH1 (0.46) PTPN1BACE1CTSD
SCHEMBL6049343 0.88 BACE1 (0.48) PTPN1GLO1BACE1EGFRCTSD
SCHEMBL6049342 0.88 BACE1 (0.48) PTPN1GLO1BACE1EGFRCTSD
SCHEMBL30099595 0.87 GLO1 (0.42) PTPN1GLO1OPRD1GNPATPTGS1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4267193-A1 IMPROVED CD30 TARGETING ANTIBODY DRUG CONJUGATES AND USES THEREOF Ludwig-Maximilians-Universität München (DE) 2023-11-01 — — EP disclosed
WO-2022136555-A9 IMPROVED CD30 TARGETING ANTIBODY DRUG CONJUGATES AND USES THEREOF LUDWIG-MAXIMILIANS-UNIVERSITAET MUENCHEN (DE) 2022-09-22 — — WO disclosed
WO-2022136555-A1 IMPROVED CD30 TARGETING ANTIBODY DRUG CONJUGATES AND USES THEREOF LUDWIG-MAXIMILIANS-UNIVERSITAET MUENCHEN (DE) 2022-06-30 — — WO disclosed
US-20220193251-A1 CD30 TARGETING ANTIBODY DRUG CONJUGATES AND USES THEREOF LUDWIG-MAXIMILIANS-UNIVERSITAET MUENCHEN (DE) 2022-06-23 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20220193251-A1 CD30 TARGETING ANTIBODY DRUG CONJUGATES AND USES THEREOF TUBB6, GALNT10, TUBB PTPN1 734/4885GLO1 2293/4885BACE1 2881/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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