Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NT5E | P21589 | 2/20 | 0.35 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.33 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.32 |
| ▸ | PDE4B | Q07343 | 2/20 | 0.30 |
| ▸ | PDE4A | P27815 | 1/20 | 0.30 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.30 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.30 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.30 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | HTT | P42858 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.30 |
| ▸ | RORC | P51449 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18526368 | 1.00 | NT5E (0.35) | NT5EOPRM1KCNH2PDE4BPDE4A | |
| SCHEMBL19956800 | 0.94 | NT5E (0.36) | NT5EOPRM1KCNH2PDE4BPDE4A | |
| SCHEMBL29406990 | 0.92 | OPRM1 (0.36) | NT5EOPRM1KCNH2HDAC6KDM4E | |
| SCHEMBL18526374 | 0.92 | OPRM1 (0.36) | NT5EOPRM1KCNH2HDAC6KDM4E | |
| SCHEMBL24942970 | 0.91 | NT5E (0.35) | NT5EOPRM1KCNH2RORC | |
| SCHEMBL23029077 | 0.91 | OPRM1 (0.34) | NT5EOPRM1KCNH2HDAC6KDM4E | |
| SCHEMBL30112665 | 0.91 | NT5E (0.35) | NT5EOPRM1KCNH2RORC | |
| SCHEMBL23029076 | 0.89 | OPRM1 (0.35) | NT5EOPRM1KCNH2PDE4BPDE4A | |
| SCHEMBL24942508 | 0.82 | NT5E (0.40) | NT5EOPRM1KCNH2HDAC6SMN1; SMN2 | |
| SCHEMBL30112567 | 0.82 | NT5E (0.40) | NT5EOPRM1KCNH2HDAC6SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4704922-A2 | COMPLEMENTATION-BASED TAGS AND REPORTERS FOR DUAL-MODALITY LABELING | Promega Corporation (US) | 2026-03-11 | — | — | EP | disclosed |
| US-12528944-B2 | Live-cell fluorescent mitochondrial stains | HOWARD HUGHES MEDICAL INSTITUTE (US) | 2026-01-20 | — | — | US | disclosed |
| US-12474345-B2 | Chemigenetic voltage indicators | HOWARD HUGHES MEDICAL INSTITUTE (US) | 2025-11-18 | — | — | US | disclosed |
| US-12275767-B2 | Chemigenetic calcium indicators | HOWARD HUGHES MEDICAL INSTITUTE (US) | 2025-04-15 | — | — | US | disclosed |
| EP-4519426-A2 | SPLIT MODIFIED DEHALOGENASE VARIANTS | PROMEGA CORPORATION (US) | 2025-03-12 | — | — | EP | disclosed |
| WO-2024229422-A2 | COMPLEMENTATION-BASED TAGS AND REPORTERS FOR DUAL-MODALITY LABELING | PROMEGA CORPORATION (US) | 2024-11-07 | — | — | WO | disclosed |
| US-20240368565-A1 | COMPLEMENTATION-BASED TAGS AND REPORTERS FOR DUAL-MODALITY LABELING | PROMEGA CORPORATION | 2024-11-07 | — | — | US | disclosed |
| US-12105122-B2 | Voltage indicators | HOWARD HUGHES MEDICAL INSTITUTE (US) | 2024-10-01 | — | — | US | disclosed |
| US-20240239818-A1 | COMPOUNDS AND COMPOSITIONS COMPRISING FLUOROPHORES FOR USE IN VISUALIZATION AND PURIFICATION OR MANIPULATION | HOWARD HUGHES MEDICAL INSTITUTE | 2024-07-18 | — | — | US | disclosed |
| US-20240174992-A1 | SPLIT MODIFIED DEHALOGENASE VARIANTS | PROMEGA CORPORATION | 2024-05-30 | — | — | US | disclosed |
| US-20230416320-A1 | CHEMIGENETIC CALCIUM INDICATORS | HOWARD HUGHES MEDICAL INSTITUTE | 2023-12-28 | — | — | US | disclosed |
| WO-2023215452-A2 | SPLIT MODIFIED DEHALOGENASE VARIANTS | PROMEGA CORPORATION (US) | 2023-11-09 | — | — | WO | disclosed |
| US-20230312931-A1 | LIVE-CELL FLUORESCENT MITOCHONDRIAL STAINS | INSTITUTE, HOWARD HUGHES MEDICAL | 2023-10-05 | — | — | US | disclosed |
| US-20230296649-A1 | VOLTAGE INDICATORS | HOWARD HUGHES MEDICAL INSTITUTE | 2023-09-21 | — | — | US | disclosed |
| US-11708397-B2 | Chemigenetic calcium indicators | HOWARD HUGHES MEDICAL INSTITUTE (US) | 2023-07-25 | — | — | US | disclosed |
| US-11598792-B2 | Voltage indicators | HOWARD HUGHES MEDICAL INSTITUTE (US) | 2023-03-07 | — | — | US | disclosed |
| US-20220299518-A1 | CHEMIGENETIC VOLTAGE INDICATORS | HOWARD HUGHES MEDICAL INSTITUTE | 2022-09-22 | — | — | US | disclosed |
| US-11385236-B2 | Chemigenetic voltage indicators | HOWARD HUGHES MEDICAL INSTITUTE (US) | 2022-07-12 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240239818-A1 | COMPOUNDS AND COMPOSITIONS COMPRISING FLUOROPHORES FOR USE IN VISUALIZATION AND PURIFICATION OR MANIPULATION | STAMBP, MSN, SYPL1 | NT5E 3372/4885OPRM1 4381/4885KCNH2 4751/4885 |
| US-12474345-B2 | Chemigenetic voltage indicators | CACNB2, CACNB3, CACNB1 | NT5E 2048/4885OPRM1 2872/4885KCNH2 151/4885 |
| US-11385236-B2 | Chemigenetic voltage indicators | CACNB2, CACNB3, CACNB1 | NT5E 2048/4885OPRM1 2872/4885KCNH2 151/4885 |
| US-20220299518-A1 | CHEMIGENETIC VOLTAGE INDICATORS | CACNB2, CACNB3, CACNB1 | NT5E 2048/4885OPRM1 2872/4885KCNH2 151/4885 |
| US-12528944-B2 | Live-cell fluorescent mitochondrial stains | MT-CO3, MT-CO1, COX5A | NT5E 2948/4885OPRM1 2225/4885KCNH2 584/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.