Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 3/20 | 0.56 |
| ▸ | CA2 | P00918 | 3/20 | 0.56 |
| ▸ | CA12 | O43570 | 2/20 | 0.56 |
| ▸ | CA7 | P43166 | 2/20 | 0.56 |
| ▸ | CA9 | Q16790 | 2/20 | 0.56 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.56 |
| ▸ | CA4 | P22748 | 1/20 | 0.56 |
| ▸ | ATM | Q13315 | 1/20 | 0.53 |
| ▸ | POLB | P06746 | 2/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.50 |
| ▸ | HTT | P42858 | 2/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.47 |
| ▸ | MAPT | P10636 | 2/20 | 0.47 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.47 |
| ▸ | ACR | P10323 | 1/20 | 0.47 |
| ▸ | BCHE | P06276 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | TP53 | P04637 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5696260 | 0.89 | SERPINE1 (0.43) | CA1CA2CA12CA7CA9 | |
| SCHEMBL30524282 | 0.89 | SERPINE1 (0.43) | CA1CA2CA12CA7CA9 | |
| 1,2-Dimethoxybenzene SCHEMBL27751216 | 0.84 | CA1 (0.65) | CA1CA2CA12CA7CA9 | |
| Guaiacol Carbonate SCHEMBL29750682 | 0.82 | CA1 (0.62) | CA1CA2CA12CA7CA9 | |
| SCHEMBL30909436 | 0.82 | CA1 (0.62) | CA1CA2CA12CA7CA9 | |
| SCHEMBL8579858 | 0.82 | CA1 (0.62) | CA1CA2CA12CA7CA9 | |
| Guaiacol Carbonate SCHEMBL21541 | 0.82 | CA1 (0.62) | CA1CA2CA12CA7CA9 | |
| SCHEMBL21828888 | 0.80 | CA12 (0.46) | CA1CA2CA12CA7CA9 | |
| SCHEMBL7258349 | 0.80 | ALDH1A1 (0.56) | ATMPOLBKMT2AALDH1A1 | |
| SCHEMBL3952526 | 0.80 | CA1 (0.59) | CA1CA2CA12CA7CA9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 204 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1595870-B1 | PROCESS FOR PRODUCING PHENYLALANINE DERIVATIVE HAVING QUINAZOLINEDIONE SKELETON AND INTERMEDIATE FOR THE SAME | AJINOMOTO KK (JP) | 2015-09-23 | — | — | EP | claimed |
| EP-2373633-B1 | METHOD FOR PRODUCING TRAZINE CARBAMATES USING CHLOROFORMATES | BOREALIS AGROLINZ MELAMINE (AT) | 2014-04-16 | — | — | EP | claimed |
| US-20110295001-A1 | Method for Producing Triazine Carbamates Using Chloroformates | BOREALIS AGROLINZ MELAMINE GMBH (AT) | 2011-12-01 | — | — | US | claimed |
| CN-109456324-B | Isoindoline or isoquinoline compounds, process for their preparation and pharmaceutical compositions containing them | 法国施维雅药厂 | 2022-04-22 | — | — | CN | disclosed |
| US-11028070-B2 | Isoindoline or isoquinoline compounds, a process for their preparation and pharmaceutical compositions containing them | LES LABORATOIRES SERVIER (FR) | 2021-06-08 | — | — | US | disclosed |
| US-20210070756-A1 | TETRACYCLIC BROMODOMAIN INHIBITORS | ABBVIE INC (US) | 2021-03-11 | — | — | US | disclosed |
| CN-107530349-B | Xanthine substituted alkynyl carbamates/trans carbamates as A2B antagonists | 路易斯和克拉克制药公司 | 2021-01-08 | — | — | CN | disclosed |
| US-20200291027-A1 | TETRACYCLIC BROMODOMAIN INHIBITORS | ABBVIE INC (US) | 2020-09-17 | — | — | US | disclosed |
| US-20200262816-A1 | ISOINDOLINE OR ISOQUINOLINE COMPOUNDS, A PROCESS FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | SERVIER LAB (FR) | 2020-08-20 | — | — | US | disclosed |
| EP-3280417-B1 | XANTHINE-SUBSTITUTED ALKYNYL CARBAMATES/REVERSE CARBAMATES AS A2B ANTAGONISTS | LEWIS AND CLARK PHARMACEUTICALS INC (US) | 2020-07-29 | — | — | EP | disclosed |
| US-10689364-B2 | Isoindoline or isoquinoline compounds, a process for their preparation and pharmaceutical compositions containing them | LES LABORATOIRES SERVIER (FR) | 2020-06-23 | — | — | US | disclosed |
| EP-0812835-A1 | OPTICALLY ACTIVE THIAZOLIDINONE DERIVATIVES | SANKYO COMPANY LIMITED (JP) | 1997-12-17 | — | — | EP | disclosed |
| EP-0790235-A1 | Diaryl alkane derivatives containing an alicyclic group, their preparation and their therapeutic and prophylactic uses | SANKYO COMPANY LIMITED (JP) | 1997-08-20 | — | — | EP | disclosed |
| US-4578486-A | DIOXANE | PHILIP MORRIS INCORPORATED (US) | 1986-03-25 | — | — | US | disclosed |
| US-4532944-A | Smoking compositions containing a dicarbonate ester flavorant-release additive | PHILIP MORRIS INC. (US) | 1985-08-06 | — | — | US | disclosed |
| US-4509537-A | MONOCARBONATE ESTER FLAVORANT | PHILIP MORRIS INCORPORATED (US) | 1985-04-09 | — | — | US | disclosed |
| EP-0084677-B1 | NEW COMPOUND HAVING MUCOREGULATING AND FLUIDIFYING ACTIVITY, PROCESS FOR ITS PRODUCTION AND RELATIVE PHARMACEUTICAL COMPOSITIONS | YASON S.r.l (IT) | 1985-03-27 | — | — | EP | disclosed |
| US-4415571-A | HYPOTENSIVE AGENTS; THROMBOSIS; ANTICOAGULANTS; CARDIOVASCULAR DISORDDERS | BASF AKTIENGESELLSCHAFT (DE) | 1983-11-15 | — | — | US | disclosed |
| EP-0084677-A1 | New compound having mucoregulating and fluidifying activity, process for its production and relative pharmaceutical compositions | YASON S.r.l (IT) | 1983-08-03 | — | — | EP | disclosed |
| US-4040812-A | Herbicidal carbonates and thiocarbonates of thiadiazolyl-2(1H)-pyrimidinones | VELSICOL CHEMICAL CORPORATION (US) | 1977-08-09 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200291027-A1 | TETRACYCLIC BROMODOMAIN INHIBITORS | BRD3, BRD4, BRD1 | CA1 1983/4885CA2 2280/4885CA12 2677/4885 |
| US-20210070756-A1 | TETRACYCLIC BROMODOMAIN INHIBITORS | BRD3, BRD4, BRD1 | CA1 1983/4885CA2 2280/4885CA12 2677/4885 |
| US-20110295001-A1 | Method for Producing Triazine Carbamates Using Chloroformates | CA3, CA7, KAT5 | CA1 10/4885CA2 11/4885CA12 13/4885 |
| US-20200262816-A1 | ISOINDOLINE OR ISOQUINOLINE COMPOUNDS, A PROCESS FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | BAX, RECQL, CASP7 | CA1 4869/4885CA2 4843/4885CA12 4884/4885 |
| US-10689364-B2 | Isoindoline or isoquinoline compounds, a process for their preparation and pharmaceutical compositions containing them | BAX, CASP7, CASP3 | CA1 4867/4885CA2 4839/4885CA12 4884/4885 |
| US-11028070-B2 | Isoindoline or isoquinoline compounds, a process for their preparation and pharmaceutical compositions containing them | BAX, RECQL, CASP7 | CA1 4869/4885CA2 4843/4885CA12 4884/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.