Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RORC | P51449 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 2/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | CASP3 | P42574 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.31 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.31 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.31 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.31 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.30 |
| ▸ | SLC6A9 | P48067 | 1/20 | 0.30 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | THRB | P10828 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21835709 | 0.81 | TDP1 (0.39) | RORCNPC1RAB9ANR4A1ALDH1A1 | |
| SCHEMBL21835728 | 0.81 | SMN1; SMN2 (0.39) | RORCMEN1KMT2ANPC1RAB9A | |
| SCHEMBL14937696 | 0.80 | RORC (0.43) | RORCMEN1KMT2ASLC6A4ALDH1A1 | |
| SCHEMBL18398370 | 0.77 | ALOX15 (0.42) | MEN1KMT2ANR4A1SLC6A4ALDH1A1 | |
| SCHEMBL2833080 | 0.74 | LDHA (0.42) | RORCMEN1KMT2ARAB9ASLC6A4 | |
| SCHEMBL11238 | 0.74 | TDP1 (0.43) | NPC1RAB9ANR4A1ALDH1A1MAPT | |
| SCHEMBL11433 | 0.74 | TDP1 (0.43) | NPC1RAB9ANR4A1ALDH1A1MAPT | |
| SCHEMBL10941 | 0.74 | TDP1 (0.43) | NPC1RAB9ANR4A1ALDH1A1MAPT | |
| SCHEMBL28778383 | 0.74 | MAPT (0.43) | RORCMEN1KMT2ANPC1RAB9A | |
| SCHEMBL1034163 | 0.73 | GPR3 (0.44) | NPC1RAB9ANR4A1ALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114436955-A | Tetrahydroquinoline and benzomorpholine derivatives or salts thereof, and preparation method and application thereof | 复旦大学 | 2022-05-06 | — | — | CN | disclosed |