Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.34 |
| ▸ | CASP3 | P42574 | 2/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.33 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.33 |
| ▸ | LMNA | P02545 | 3/20 | 0.33 |
| ▸ | PTGDR2 | Q9Y5Y4 | 2/20 | 0.33 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.33 |
| ▸ | USP2 | O75604 | 1/20 | 0.33 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 2/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.32 |
| ▸ | POLB | P06746 | 2/20 | 0.32 |
| ▸ | PKM | P14618 | 1/20 | 0.32 |
| ▸ | GABRP | O00591 | 1/20 | 0.32 |
| ▸ | GABRD | O14764 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.32 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29059216 | 0.90 | CASP3 (0.35) | TSHRCASP3CYP1A2CYP2C19SMN1; SMN2 | |
| SCHEMBL29761323 | 0.81 | CASP3 (0.38) | TSHRCASP3CYP1A2CYP2C19SMN1; SMN2 | |
| SCHEMBL29761325 | 0.78 | MIF (0.34) | TSHRCASP3CYP1A2CYP2C19SMN1; SMN2 | |
| SCHEMBL29058636 | 0.70 | SMN1; SMN2 (0.37) | SMN1; SMN2LMNAMEN1KMT2AALDH1A1 | |
| SCHEMBL29058598 | 0.67 | LMNA (0.32) | SMN1; SMN2LMNAMEN1KMT2APOLB | |
| SCHEMBL29761331 | 0.65 | MMP1 (0.34) | SMN1; SMN2LMNAMEN1KMT2APOLB | |
| SCHEMBL29761328 | 0.64 | POLB (0.35) | SMN1; SMN2LMNAMEN1KMT2APOLB | |
| SCHEMBL29761324 | 0.64 | SMN1; SMN2 (0.37) | SMN1; SMN2LMNAMEN1KMT2APOLB | |
| SCHEMBL29058642 | 0.63 | SMN1; SMN2 (0.38) | SMN1; SMN2LMNAMEN1KMT2APOLB | |
| SCHEMBL510389 | 0.63 | MAPT (0.32) | SMN1; SMN2LMNAHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4267556-A1 | SUBSTITUTED PYRIDAZINONE HERBICIDES | FMC CORPORATION (US) | 2023-11-01 | — | — | EP | disclosed |
| WO-2022140309-A1 | SUBSTITUTED PYRIDAZINONE HERBICIDES | FMC CORPORTION (US) | 2022-06-30 | — | — | WO | disclosed |