Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR7 | P34969 | 5/20 | 0.54 |
| ▸ | HTR1A | P08908 | 3/20 | 0.54 |
| ▸ | HTR2A | P28223 | 1/20 | 0.54 |
| ▸ | HTR5A | P47898 | 1/20 | 0.54 |
| ▸ | HTR6 | P50406 | 1/20 | 0.54 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | EGFR | P00533 | 1/20 | 0.47 |
| ▸ | RAF1 | P04049 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.47 |
| ▸ | MAP2K1 | Q02750 | 1/20 | 0.47 |
| ▸ | FEN1 | P39748 | 1/20 | 0.46 |
| ▸ | DHFR | P00374 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.43 |
| ▸ | SMYD2 | Q9NRG4 | 1/20 | 0.41 |
| ▸ | PRKDC | P78527 | 3/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5352962 | 0.87 | HTR7 (0.69) | HTR7HTR1AHTR2AHTR5AHTR6 | |
| SCHEMBL13039956 | 0.85 | HTR7 (0.67) | HTR7HTR1AHTR2AHTR5AHTR6 | |
| SCHEMBL27876080 | 0.85 | HTR7 (0.67) | HTR7HTR1AHTR2AHTR5AHTR6 | |
| Hydrochloric Acid SCHEMBL27892728 | 0.83 | HTR7 (0.65) | HTR7HTR1AHTR2AHTR5AHTR6 | |
| SCHEMBL17857889 | 0.76 | HTR1A (0.53) | HTR7HTR1AL3MBTL1MAPK1ALDH1A1 | |
| SCHEMBL30146696 | 0.76 | HTR7 (0.63) | HTR7HTR1AHTR2AHTR5AHTR6 | |
| SCHEMBL27497441 | 0.73 | HTR1A (0.70) | HTR7HTR1AMAPK1ALDH1A1DHFR | |
| SCHEMBL28281276 | 0.73 | PTGS2 (0.54) | HTR7HTR1AHTR2AHTR5AHTR6 | |
| SCHEMBL23708148 | 0.71 | ALOX5 (0.52) | L3MBTL1MAPK1ALDH1A1MAPTALOX12 | |
| SCHEMBL23708081 | 0.71 | KDM4E (0.43) | HTR7HTR1AL3MBTL1MAPK1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2854802-B2 | TOPICAL OIL IN WATER EMULSION COMPOSITIONS COMPRISING A RETINOID | GALDERMA RES & DEV (FR) | 2022-08-24 | — | — | EP | disclosed |