Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 1/20 | 0.52 |
| ▸ | BACE1 | P56817 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 2/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | HNF4A | P41235 | 2/20 | 0.44 |
| ▸ | ACMSD | Q8TDX5 | 2/20 | 0.44 |
| ▸ | GBA1 | P04062 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 3/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | HTT | P42858 | 2/20 | 0.43 |
| ▸ | USP2 | O75604 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.43 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23708525 | 0.79 | NR1I2 (0.43) | HPGDMAPK1LMNAMAPTHTT | |
| SCHEMBL23708081 | 0.79 | KDM4E (0.43) | HPGDMAPK1KDM4EMAPTALDH1A1 | |
| SCHEMBL23708502 | 0.79 | KEAP1 (0.56) | HPGDMAPK1LMNAKDM4EMEN1 | |
| SCHEMBL23708307 | 0.78 | ALDH1A1 (0.40) | HPGDMAPK1LMNAKDM4EMEN1 | |
| SCHEMBL23707895 | 0.76 | KDM4E (0.63) | HPGDMAPK1HNF4AACMSDLMNA | |
| SCHEMBL23708171 | 0.75 | NCF1 (0.48) | BACE1LMNAKDM4EMEN1KMT2A | |
| SCHEMBL23708324 | 0.75 | ALDH1A1 (0.57) | HPGDMAPK1GBA1KDM4EMEN1 | |
| SCHEMBL16793286 | 0.75 | AR (0.59) | HPGDLMNAKDM4EMEN1KMT2A | |
| SCHEMBL23708106 | 0.75 | ALDH1A1 (0.43) | BACE1HPGDMAPK1LMNAKDM4E | |
| SCHEMBL1010647 | 0.74 | GAA (0.60) | HPGDMAPK1MEN1KMT2AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021154966-A1 | COMPOUNDS AND COMPOSITIONS FOR USE IN TREATING SKIN DISORDERS | KAMARI PHARMA LTD. (IL) | 2021-08-05 | — | — | WO | disclosed |