SCHEMBL29771981

SCHEMBL29771981

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nearest known ligand 0.51

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
▸ TASP1 Q9H6P5 1/20 0.51
▸ BACE1 P56817 4/20 0.47
▸ GRIN2D O15399 1/20 0.47
▸ GRIN3B O60391 1/20 0.47
▸ GRIN1 Q05586 1/20 0.47
▸ GRIN2A Q12879 1/20 0.47
▸ GRIN2B Q13224 1/20 0.47
▸ GRIN2C Q14957 1/20 0.47
▸ GRIN3A Q8TCU5 1/20 0.47
▸ ENPEP Q07075 5/20 0.43
▸ RXFP1 Q9HBX9 1/20 0.41
▸ PTH1R Q03431 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30810283 0.92 TASP1 (0.49) TASP1BACE1GRIN2DGRIN3BGRIN1
SCHEMBL29772026 0.91 FOLH1 (0.45) TASP1BACE1
SCHEMBL29777878 0.90 GRIN2D (0.55) TASP1BACE1GRIN2DGRIN3BGRIN1
SCHEMBL29772029 0.89 OPRM1 (0.46) TASP1BACE1GRIN2DGRIN3BGRIN1
SCHEMBL29771973 0.89 FOLH1 (0.44) TASP1BACE1
SCHEMBL29405906 0.89 TASP1 (0.55) TASP1BACE1GRIN2DGRIN3BGRIN1
SCHEMBL29772030 0.88 EGFR (0.47) BACE1
SCHEMBL31670475 0.88 ENPEP (0.49) TASP1BACE1ENPEP
SCHEMBL29771991 0.88 BACE1 (0.48) TASP1BACE1ENPEP
SCHEMBL29772133 0.87 FOLH1 (0.49) BACE1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12221494-B2 Short synthetic peptides and their uses for treating retinal degenerative diseases and/or tissue injuries MACKAY MEMORIAL HOSPITAL (TW) 2025-02-11 — — US disclosed
US-20220204559-A1 SHORT SYNTHETIC PEPTIDES AND THEIR USES FOR TREATING RETINAL DEGENERATIVE DISEASES AND/OR TISSUE INJURIES MACKAY MEMORIAL HOSPITAL (TW) 2022-06-30 — — US disclosed
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