Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 3/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 3/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.34 |
| ▸ | HPGD | P15428 | 2/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.34 |
| ▸ | GRM5 | P41594 | 2/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29777621 | 0.83 | CYP2C19 (0.37) | POLBGAALMNANPC1RAB9A | |
| SCHEMBL22421130 | 0.80 | MAP3K14 (0.34) | POLBGAALMNANPC1RAB9A | |
| SCHEMBL29777574 | 0.79 | POLB (0.41) | POLBGAALMNANPC1RAB9A | |
| SCHEMBL20400203 | 0.78 | NLRP3 (0.38) | GAALMNAALDH1A1KDM4EHTT | |
| SCHEMBL22421167 | 0.75 | RAB9A (0.46) | POLBGAALMNANPC1RAB9A | |
| SCHEMBL15882234 | 0.69 | VCAM1 (0.39) | POLBGAALMNARAB9AALDH1A1 | |
| SCHEMBL22421148 | 0.68 | ALDH1A1 (0.33) | ALDH1A1HTTMAPK1 | |
| SCHEMBL29777626 | 0.66 | PKM (0.35) | LMNAALDH1A1SMN1; SMN2HTTKMT2A | |
| SCHEMBL28667528 | 0.66 | ALDH1A1 (0.40) | POLBGAALMNAALDH1A1KDM4E | |
| SCHEMBL29777572 | 0.65 | KDM4E (0.35) | POLBGAALMNAALDH1A1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108948019-B | Focal adhesion kinase inhibitors and uses thereof | 广东东阳光药业有限公司 | 2022-07-08 | — | — | CN | disclosed |