Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX15 | P16050 | 1/20 | 0.34 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.33 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.33 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | DRD2 | P14416 | 1/20 | 0.31 |
| ▸ | WNT1 | P04628 | 2/20 | 0.31 |
| ▸ | GSK3B | P49841 | 2/20 | 0.31 |
| ▸ | DYRK1A | Q13627 | 2/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.30 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.30 |
| ▸ | PTPN5 | P54829 | 1/20 | 0.30 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.30 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29777616 | 0.80 | MAP4K4 (0.36) | ALOX15ALDH1A1KDM4EPRMT5WDR77 | |
| SCHEMBL16469156 | 0.74 | LRRK2 (0.39) | ALOX15WNT1GSK3BDYRK1APRMT5 | |
| SCHEMBL28558608 | 0.69 | CREBBP (0.34) | PRMT5WDR77 | |
| SCHEMBL5418762 | 0.69 | ALDH1A1 (0.39) | ALOX15ROCK2ROCK1CYP2C19MEN1 | |
| SCHEMBL20939544 | 0.67 | PRMT5 (0.41) | MEN1KMT2AALDH1A1KDM4EPRMT5 | |
| SCHEMBL16469651 | 0.65 | — | — | |
| SCHEMBL29777611 | 0.65 | LMNA (0.36) | CYP2C19KMT2ACYP3A4TSHRALDH1A1 | |
| SCHEMBL27249876 | 0.65 | PRMT5 (0.40) | DRD2PRMT5WDR77 | |
| SCHEMBL5421915 | 0.64 | ALOX15 (0.36) | ALOX15ROCK2ROCK1CYP2C19MEN1 | |
| SCHEMBL17045302 | 0.64 | CYP11B1 (0.40) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108948019-B | Focal adhesion kinase inhibitors and uses thereof | 广东东阳光药业有限公司 | 2022-07-08 | — | — | CN | disclosed |