Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR3A | P46098 | 4/20 | 0.73 |
| ▸ | DRD2 | P14416 | 2/20 | 0.73 |
| ▸ | HTR3E | A5X5Y0 | 2/20 | 0.73 |
| ▸ | HTR3B | O95264 | 2/20 | 0.73 |
| ▸ | HTR3D | Q70Z44 | 2/20 | 0.73 |
| ▸ | HTR3C | Q8WXA8 | 2/20 | 0.73 |
| ▸ | ADRB1 | P08588 | 2/20 | 0.73 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.73 |
| ▸ | DRD3 | P35462 | 1/20 | 0.73 |
| ▸ | HTR6 | P50406 | 1/20 | 0.73 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.73 |
| ▸ | LMNA | P02545 | 1/20 | 0.71 |
| ▸ | MAPT | P10636 | 1/20 | 0.71 |
| ▸ | HTR1A | P08908 | 4/20 | 0.68 |
| ▸ | HTR7 | P34969 | 4/20 | 0.66 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.51 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.51 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.51 |
| ▸ | HTR2B | P41595 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5363594 | 1.00 | HTR3A (0.73) | HTR3ADRD2HTR3EHTR3BHTR3D | |
| SCHEMBL27261438 | 0.85 | ADRB1 (0.57) | HTR3ADRD2HTR3EHTR3BHTR3D | |
| SCHEMBL8109063 | 0.85 | HTR3A (0.60) | HTR3ADRD2HTR3EHTR3BHTR3D | |
| SCHEMBL379 | 0.84 | HTR3A (1.00) | HTR3ADRD2HTR3EHTR3BHTR3D | |
| SCHEMBL29396943 | 0.84 | HTR3A (1.00) | HTR3ADRD2HTR3EHTR3BHTR3D | |
| SCHEMBL7310094 | 0.84 | KMT2A (0.54) | HTR3ADRD2HTR3EHTR3BHTR3D | |
| SCHEMBL6366499 | 0.84 | HTR3A (1.00) | HTR3ADRD2HTR3EHTR3BHTR3D | |
| SCHEMBL31348240 | 0.83 | ADRB1 (0.65) | HTR3ADRD2HTR3EHTR3BHTR3D | |
| SCHEMBL5372329 | 0.83 | HTR6 (0.73) | HTR3ADRD2HTR3EHTR3BHTR3D | |
| Hydrochloric Acid SCHEMBL6602545 | 0.83 | LMNA (1.00) | HTR3ADRD2HTR3EHTR3BHTR3D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111377846-B | Piperazine benzamide derivative and application thereof | 江苏恩华药业股份有限公司 | 2022-05-24 | — | — | CN | disclosed |