Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.60 |
| ▸ | POLB | P06746 | 3/20 | 0.60 |
| ▸ | LMNA | P02545 | 2/20 | 0.60 |
| ▸ | HPGD | P15428 | 1/20 | 0.60 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.60 |
| ▸ | ACLY | P53396 | 3/20 | 0.55 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | APAF1 | O14727 | 1/20 | 0.50 |
| ▸ | GRK2 | P25098 | 1/20 | 0.50 |
| ▸ | S100A4 | P26447 | 1/20 | 0.50 |
| ▸ | CASP6 | P55212 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.50 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.50 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.49 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.49 |
| ▸ | USP2 | O75604 | 1/20 | 0.49 |
| ▸ | TP53 | P04637 | 1/20 | 0.49 |
| ▸ | TSHR | P16473 | 1/20 | 0.49 |
| ▸ | RAB9A | P51151 | 1/20 | 0.49 |
| ▸ | WDR5 | P61964 | 3/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2994570 | 0.83 | ALDH1A1 (0.79) | ALDH1A1POLBLMNAHPGDL3MBTL1 | |
| SCHEMBL4836486 | 0.82 | ALDH1A1 (0.56) | ALDH1A1POLBLMNAHPGDL3MBTL1 | |
| SCHEMBL2987399 | 0.81 | ACLY (0.60) | ALDH1A1POLBACLYMEN1KMT2A | |
| SCHEMBL23833756 | 0.75 | POLB (0.56) | ALDH1A1POLBLMNAHPGDL3MBTL1 | |
| SCHEMBL3248880 | 0.75 | LMNA (0.69) | ALDH1A1POLBLMNAHPGDL3MBTL1 | |
| SCHEMBL8752412 | 0.75 | L3MBTL1 (1.00) | ALDH1A1POLBLMNAHPGDL3MBTL1 | |
| SCHEMBL2992284 | 0.74 | ALDH1A1 (0.67) | ALDH1A1POLBLMNAHPGDL3MBTL1 | |
| SCHEMBL27182666 | 0.74 | ALDH1A1 (0.67) | ALDH1A1POLBLMNAHPGDL3MBTL1 | |
| SCHEMBL13265920 | 0.74 | HPGD (0.57) | ALDH1A1POLBLMNAHPGDL3MBTL1 | |
| SCHEMBL2986118 | 0.74 | ACLY (0.53) | ALDH1A1LMNAACLYMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100179168-A1 | ARYL AND HETEROARYL SULPHONAMIDES AS GROWTH HORMONE SECRETAGOGUE RECEPTOR AGONISTS | BLANEY EMMA LOUISE | 2010-07-15 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100179168-A1 | ARYL AND HETEROARYL SULPHONAMIDES AS GROWTH HORMONE SECRETAGOGUE RECEPTOR AGONISTS | GHSR, GHRHR, GIPR | ALDH1A1 2521/4885POLB 4727/4885LMNA 4700/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.