SCHEMBL29904042

SCHEMBL29904042

C[C@H](NC(=O)[C@@H]1CCCN1C(=O)[C@H](CCC(N)=O)NC(=O)[C@@H]1CCCN1C(=O)CN)C(=O)NCC(=O)N[C@@H](CCC(N)=O)C(=O)O

nearest known ligand 0.42

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
▸ APLNR P35414 1/20 0.42
▸ OPRM1 P35372 2/20 0.41
▸ OPRD1 P41143 2/20 0.41
▸ NTSR1 P30989 1/20 0.40
▸ NMUR2 Q9GZQ4 3/20 0.40
▸ NMUR1 Q9HB89 3/20 0.40
▸ PTPN1 P18031 1/20 0.39
▸ GRB2 P62993 1/20 0.39
▸ F2 P00734 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30493464 0.93 APLNR (0.42) APLNROPRM1OPRD1NMUR2NMUR1
SCHEMBL29904041 0.93 APLNR (0.41) APLNROPRM1OPRD1NTSR1NMUR2
SCHEMBL29800494 0.89 OPRM1 (0.44) APLNROPRM1OPRD1NMUR2NMUR1
SCHEMBL29641591 0.89 KEAP1 (0.49) PTPN1
SCHEMBL29800885 0.87 NAA50 (0.47) APLNROPRM1OPRD1NTSR1NMUR2
SCHEMBL29569246 0.86 NTSR1 (0.44) APLNROPRD1NTSR1PTPN1F2
SCHEMBL29800900 0.86 NTSR1 (0.48) OPRD1NTSR1PTPN1F2
SCHEMBL29493717 0.84 NTSR2 (0.42) APLNROPRM1OPRD1NTSR1F2
SCHEMBL4726312 0.84 APLNR (0.40) APLNROPRM1OPRD1PTPN1GRB2
SCHEMBL4726314 0.84 APLNR (0.40) APLNROPRM1OPRD1PTPN1GRB2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12569575-B2 Radiopaque particle compositions and uses thereof GUSTAVE ROUSSY TRANSFERT (FR) 2026-03-10 — — US disclosed
US-20240108781-A1 POLYMERIC TREATMENT COMPOSITIONS MICROVENTION, INC. 2024-04-04 — — US disclosed
US-11801326-B2 Polymeric treatment compositions MICROVENTION, INC. (US) 2023-10-31 — — US disclosed
US-20220273825-A1 RADIOPAQUE PARTICLE COMPOSITIONS AND USES THEREOF GUSTAVE ROUSSY TRANSFERT (FR) 2022-09-01 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12569575-B2 Radiopaque particle compositions and uses thereof PDGFRB, ERBB2, AKT1 APLNR 1990/4885OPRM1 1480/4885OPRD1 2334/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

Send feedback