Sugi Predict

Sugi Predict / Compounds / SCHEMBL29801554

SCHEMBL29801554

SCHEMBL29801554

O=C1N=C(Nc2ccccc2C(=O)O)S/C1=C/c1c[nH]c2ccccc12

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ MEN1 O00255 8/20 0.39
▸ KMT2A Q03164 8/20 0.39
▸ MAPT P10636 6/20 0.39
▸ ALDH1A1 P00352 5/20 0.39
▸ TDP1 Q9NUW8 3/20 0.39
▸ HTT P42858 1/20 0.39
▸ RAB9A P51151 4/20 0.39
▸ NPC1 O15118 3/20 0.39
▸ PTGS1 P23219 1/20 0.39
▸ PTGS2 P35354 1/20 0.39
▸ GAA P10253 1/20 0.38
▸ CASP3 P42574 1/20 0.38
▸ KLF5 Q13887 1/20 0.38
▸ SENP8 Q96LD8 1/20 0.38
▸ SENP7 Q9BQF6 1/20 0.38
▸ SENP6 Q9GZR1 1/20 0.38
▸ KDM4E B2RXH2 4/20 0.38
▸ LMNA P02545 3/20 0.38
▸ HPGD P15428 3/20 0.38
▸ SMN1; SMN2 Q16637 2/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21048269 1.00 MEN1 (0.39) MEN1KMT2AMAPTALDH1A1TDP1
SCHEMBL23361928 1.00 MEN1 (0.39) MEN1KMT2AMAPTALDH1A1TDP1
SCHEMBL19859238 0.84 ALDH1A1 (0.42) MEN1KMT2AMAPTALDH1A1HTT
SCHEMBL29801609 0.84 ALDH1A1 (0.42) MEN1KMT2AMAPTALDH1A1HTT
SCHEMBL21074335 0.84 MAPT (0.45) MEN1KMT2AMAPTALDH1A1HTT
SCHEMBL29801729 0.84 PRKCB (0.44) MEN1KMT2AMAPTALDH1A1TDP1
SCHEMBL21074348 0.84 PRKCB (0.44) MEN1KMT2AMAPTALDH1A1TDP1
SCHEMBL29801683 0.83 SENP7 (0.44) MEN1KMT2AMAPTALDH1A1TDP1
SCHEMBL19859149 0.83 SENP7 (0.44) MEN1KMT2AMAPTALDH1A1TDP1
SCHEMBL23361942 0.83 MEN1 (0.44) MEN1KMT2AMAPTALDH1A1TDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-114929217-A Pharmaceutical composition for treating multiple sclerosis based on AMPK inhibitory function and zinc homeostasis control function 锌医疗公司 2022-08-19 — — CN claimed
US-12343335-B2 Pharmaceutical composition for treating multiple sclerosis on basis of AMPK inhibitory function and zinc homeostasis control function ZINCURE CORP. (KR) 2025-07-01 — — US disclosed
US-20230000839-A1 PHARMACEUTICAL COMPOSITION FOR TREATING MULTIPLE SCLEROSIS ON BASIS OF AMPK INHIBITORY FUNCTION AND ZINC HOMEOSTASIS CONTROL FUNCTION ZINCURE CORP. (KR) 2023-01-05 — — US disclosed
CN-114929217-A Pharmaceutical composition for treating multiple sclerosis based on AMPK inhibitory function and zinc homeostasis control function 锌医疗公司 2022-08-19 — — CN disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230000839-A1 PHARMACEUTICAL COMPOSITION FOR TREATING MULTIPLE SCLEROSIS ON BASIS OF AMPK INHIBITORY FUNCTION AND ZINC HOMEOSTASIS CONTROL FUNCTION PRKAB1, PRKAB2, PRKAG1 MEN1 3953/4885KMT2A 2170/4885MAPT 517/4885
US-12343335-B2 Pharmaceutical composition for treating multiple sclerosis on basis of AMPK inhibitory function and zinc homeostasis control function PRKAB1, PRKAB2, PRKAG1 MEN1 3953/4885KMT2A 2170/4885MAPT 517/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.