Sugi Predict

Sugi Predict / Compounds / SCHEMBL29801796

SCHEMBL29801796

SCHEMBL29801796

Cc1ccc(NC2=NC(=O)/C(=C/c3c[nH]c4ccccc34)S2)cc1

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ SENP7 Q9BQF6 3/20 0.48
▸ SENP8 Q96LD8 2/20 0.48
▸ SENP6 Q9GZR1 2/20 0.48
▸ CASP3 P42574 2/20 0.48
▸ PRKCB P05771 1/20 0.45
▸ MAPT P10636 12/20 0.43
▸ MEN1 O00255 9/20 0.43
▸ KMT2A Q03164 9/20 0.43
▸ PTGS2 P35354 1/20 0.43
▸ SMN1; SMN2 Q16637 4/20 0.42
▸ GAA P10253 2/20 0.42
▸ KDM4E B2RXH2 6/20 0.42
▸ ALDH1A1 P00352 5/20 0.42
▸ LMNA P02545 6/20 0.42
▸ HPGD P15428 3/20 0.42
▸ NPC1 O15118 3/20 0.42
▸ RAB9A P51151 3/20 0.42
▸ CYP1A2 P05177 1/20 0.42
▸ CYP3A4 P08684 1/20 0.42
▸ CYP2D6 P10635 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19859241 1.00 SENP7 (0.48) SENP7SENP8SENP6CASP3PRKCB
SCHEMBL19859149 0.91 SENP7 (0.44) SENP7SENP8SENP6CASP3PRKCB
SCHEMBL29801683 0.91 SENP7 (0.44) SENP7SENP8SENP6CASP3PRKCB
SCHEMBL29801391 0.89 SENP8 (0.52) SENP7SENP8SENP6CASP3PRKCB
SCHEMBL21074342 0.89 SENP8 (0.52) SENP7SENP8SENP6CASP3PRKCB
SCHEMBL21074343 0.89 BACE1 (0.43) SENP7SENP8SENP6CASP3MAPT
SCHEMBL23362519 0.88 STING1 (0.43) SENP7SENP8SENP6CASP3PRKCB
SCHEMBL21074334 0.88 STING1 (0.43) SENP7SENP8SENP6CASP3PRKCB
SCHEMBL29801442 0.88 STING1 (0.43) SENP7SENP8SENP6CASP3PRKCB
SCHEMBL21074328 0.85 LMNA (0.40) SENP7SENP8SENP6CASP3MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-114929217-A Pharmaceutical composition for treating multiple sclerosis based on AMPK inhibitory function and zinc homeostasis control function 锌医疗公司 2022-08-19 — — CN claimed
US-12343335-B2 Pharmaceutical composition for treating multiple sclerosis on basis of AMPK inhibitory function and zinc homeostasis control function ZINCURE CORP. (KR) 2025-07-01 — — US disclosed
US-20230000839-A1 PHARMACEUTICAL COMPOSITION FOR TREATING MULTIPLE SCLEROSIS ON BASIS OF AMPK INHIBITORY FUNCTION AND ZINC HOMEOSTASIS CONTROL FUNCTION ZINCURE CORP. (KR) 2023-01-05 — — US disclosed
CN-114929217-A Pharmaceutical composition for treating multiple sclerosis based on AMPK inhibitory function and zinc homeostasis control function 锌医疗公司 2022-08-19 — — CN disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230000839-A1 PHARMACEUTICAL COMPOSITION FOR TREATING MULTIPLE SCLEROSIS ON BASIS OF AMPK INHIBITORY FUNCTION AND ZINC HOMEOSTASIS CONTROL FUNCTION PRKAB1, PRKAB2, PRKAG1 SENP7 1041/4885SENP8 1309/4885SENP6 1528/4885
US-12343335-B2 Pharmaceutical composition for treating multiple sclerosis on basis of AMPK inhibitory function and zinc homeostasis control function PRKAB1, PRKAB2, PRKAG1 SENP7 1041/4885SENP8 1309/4885SENP6 1528/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.