SCHEMBL2980435

SCHEMBL2980435

CNC(=O)CN(CC1CCN(CCCc2ccc(OC)cc2)CC1)C(=O)O

nearest known ligand 0.51

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
KCNA3 P22001 1/20 0.51
C5AR1 P21730 1/20 0.51
DRD2 P14416 1/20 0.49
KDM1A O60341 2/20 0.49
HDAC6 Q9UBN7 2/20 0.49
SIGMAR1 Q99720 2/20 0.48
OPRM1 P35372 3/20 0.47
LTA4H P09960 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2980152 0.86 C5AR1 (0.62) KCNA3C5AR1DRD2KDM1AHDAC6
SCHEMBL2981930 0.85 DRD3 (0.46) SIGMAR1OPRM1LTA4H
SCHEMBL2982100 0.82 CCR3 (0.42) DRD2KDM1ASIGMAR1OPRM1
SCHEMBL2970396 0.79 DRD4 (0.47) SIGMAR1
SCHEMBL2983973 0.78 SIGMAR1 (0.51) DRD2SIGMAR1LTA4H
SCHEMBL2973384 0.78 BCHE (0.52)
SCHEMBL3604725 0.78 LTA4H (0.60) KCNA3C5AR1DRD2KDM1AHDAC6
SCHEMBL2970167 0.77 SIGMAR1 (0.49) SIGMAR1
SCHEMBL3604727 0.76 C5AR1 (0.60) KCNA3C5AR1DRD2SIGMAR1OPRM1
SCHEMBL2975084 0.76 CACNA1G (0.41)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7781590-B2 Piperidinylalkylcarbamate derivatives, methods for their preparation and the therapeutic use thereof as fatty acid amido hydrolase enzyme inhibitors SANOFI-AVENTIS (FR) 2010-08-24 US disclosed
US-20070021403-A1 PIPERIDINYLALKYLCARBAMATE DERIVATIVES, METHODS FOR THEIR PREPARATION AND THE THERAPEUTIC USE THEREOF AS FATTY ACID AMIDO HYDROLASE ENZYME INHIBITORS SANOFI-AVENTIS (FR) 2007-01-25 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20070021403-A1 PIPERIDINYLALKYLCARBAMATE DERIVATIVES, METHODS FOR THEIR PREPARATION AND THE THERAPEUTIC USE THEREOF AS FATTY ACID AMIDO HYDROLASE ENZYME INHIBITORS FAAH, FAAH2, CNR2 KCNA3 793/4885C5AR1 1847/4885DRD2 1610/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.