Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.41 |
| ▸ | ELANE | P08246 | 6/20 | 0.38 |
| ▸ | CTSG | P08311 | 3/20 | 0.38 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.34 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 2/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | FAAH | O00519 | 3/20 | 0.31 |
| ▸ | MGLL | Q99685 | 1/20 | 0.31 |
| ▸ | F2 | P00734 | 3/20 | 0.31 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.31 |
| ▸ | ERN1 | O75460 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9384378 | 0.82 | SIGMAR1 (0.39) | SIGMAR1ELANECTSGCYP19A1CHRM1 | |
| SCHEMBL9131625 | 0.81 | CYP19A1 (0.42) | SIGMAR1ELANECTSGCYP19A1CHRM1 | |
| SCHEMBL15275741 | 0.76 | RAB9A (0.40) | SIGMAR1ELANECTSGCYP19A1CHRM1 | |
| SCHEMBL15322317 | 0.76 | RAB9A (0.39) | SIGMAR1ELANECTSGCYP19A1CHRM1 | |
| SCHEMBL6771271 | 0.76 | SIGMAR1 (0.34) | SIGMAR1ELANECTSG | |
| SCHEMBL5702051 | 0.74 | RAB9A (0.48) | SIGMAR1ELANECTSGCYP19A1CHRM1 | |
| SCHEMBL14458907 | 0.74 | ALDH1A1 (0.38) | SIGMAR1ELANECTSGCYP19A1CHRM1 | |
| SCHEMBL7877679 | 0.74 | RAB9A (0.48) | SIGMAR1ELANECTSGCYP19A1CHRM1 | |
| SCHEMBL5702004 | 0.74 | RAB9A (0.48) | SIGMAR1ELANECTSGCYP19A1CHRM1 | |
| SCHEMBL2769691 | 0.74 | CYP19A1 (0.48) | SIGMAR1ELANECTSGCYP19A1CHRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1950198-B1 | PROCESS FOR PRODUCTION OF BENZYLOXYPYRROLIDINE DERIVATIVE, AND PROCESS FOR PRODUCTION OF HYDROCHLORIDE SALT POWDER OF OPTICALLY ACTIVE BENZYLOXYPYRROLIDINE DERIVATIVE | TORAY FINECHEMICALS CO LTD (JP) | 2014-08-06 | — | — | EP | disclosed |
| CN-101300228-B | Process for production of benzyloxypyrrolidine derivative, and process for production of hydrochloride salt powder of optically active benzyloxypyrrolidine derivative | TORAY FINECHEMICALS CO LTD | 2013-05-08 | — | — | CN | disclosed |
| US-7772406-B2 | Process for production of benzyloxypyrrolidine derivative, and process for production of hydrochloride salt powder of optically active benzyloxypyrrolidine derivative | TORAY FINE CHEMICALS CO., LTD. (JP) | 2010-08-10 | — | — | US | disclosed |
| US-20090093643-A1 | Process for Production of Benzyloxypyrrolidine Derivative, and Process for Production of Hydrochloride Salt Powder of Optically Active Benzyloxypyrrolidine Derivative | TORAY FINE CHEMICALS CO., LTD. (JP) | 2009-04-09 | — | — | US | disclosed |
| CN-101300228-A | Process for production of benzyloxypyrrolidine derivative, and process for production of hydrochloride salt powder of optically active benzyloxypyrrolidine derivative | TORAY FINECHEMICALS CO LTD (JP) | 2008-11-05 | — | — | CN | disclosed |
| EP-1950198-A1 | PROCESS FOR PRODUCTION OF BENZYLOXYPYRROLIDINE DERIVATIVE, AND PROCESS FOR PRODUCTION OF HYDROCHLORIDE SALT POWDER OF OPTICALLY ACTIVE BENZYLOXYPYRROLIDINE DERIVATIVE | Toray Fine Chemicals Co., Ltd. (JP) | 2008-07-30 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090093643-A1 | Process for Production of Benzyloxypyrrolidine Derivative, and Process for Production of Hydrochloride Salt Powder of Optically Active Benzyloxypyrrolidine Derivative | HPD, PAH, DHPS | SIGMAR1 1432/4885ELANE 4507/4885CTSG 3381/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.