Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | QPCT | Q16769 | 1/20 | 0.39 |
| ▸ | QPCTL | Q9NXS2 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 6/20 | 0.36 |
| ▸ | CRHR1 | P34998 | 1/20 | 0.35 |
| ▸ | METAP2 | P50579 | 1/20 | 0.35 |
| ▸ | PLAU | P00749 | 1/20 | 0.35 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.34 |
| ▸ | ABL1 | P00519 | 1/20 | 0.34 |
| ▸ | EGFR | P00533 | 1/20 | 0.34 |
| ▸ | HCK | P08631 | 1/20 | 0.34 |
| ▸ | SRC | P12931 | 1/20 | 0.34 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.34 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.34 |
| ▸ | MTOR | P42345 | 1/20 | 0.34 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.34 |
| ▸ | EPHB4 | P54760 | 1/20 | 0.34 |
| ▸ | PRKDC | P78527 | 1/20 | 0.34 |
| ▸ | PI4KB | Q9UBF8 | 1/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1471865 | 1.00 | QPCT (0.39) | QPCTQPCTLGAACYP1A2CRHR1 | |
| SCHEMBL18399189 | 0.80 | CYP1A2 (0.37) | QPCTQPCTLCYP1A2PIK3CAKMT2A | |
| SCHEMBL28323180 | 0.78 | CYP1A2 (0.45) | CYP1A2PIK3CAKMT2AMEN1ALDH1A1 | |
| SCHEMBL19103239 | 0.78 | P2RX3 (0.37) | KMT2ALRRK2 | |
| SCHEMBL17541424 | 0.77 | FTO (0.39) | CYP1A2KMT2AMEN1ALDH1A1FTO | |
| SCHEMBL1180511 | 0.77 | NUDT1 (0.44) | CYP1A2METAP2KMT2AALDH1A1KDM4E | |
| SCHEMBL2817366 | 0.77 | ALDH1A1 (0.43) | GAACYP1A2KMT2AALDH1A1KDM4E | |
| SCHEMBL13460628 | 0.76 | DHFR (0.43) | LRRK2TSHR | |
| SCHEMBL8888 | 0.76 | QPCT (0.40) | QPCTQPCTLGAACYP1A2CRHR1 | |
| SCHEMBL3816071 | 0.76 | KMT2A (0.52) | QPCTQPCTLCYP1A2CRHR1METAP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114835687-B | AhR inhibitors | 北京华森英诺生物科技有限公司 | 2023-09-05 | — | — | CN | disclosed |
| CN-114835687-A | AhR inhibitors | 重庆华森制药股份有限公司 | 2022-08-02 | — | — | CN | disclosed |