Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPBAR1 | Q8TDU6 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
| ▸ | ACHE | P22303 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | CYSLTR1 | Q9Y271 | 1/20 | 0.35 |
| ▸ | GRM5 | P41594 | 3/20 | 0.35 |
| ▸ | CBX7 | O95931 | 2/20 | 0.34 |
| ▸ | CDYL2 | Q8N8U2 | 2/20 | 0.34 |
| ▸ | CDYL | Q9Y232 | 2/20 | 0.34 |
| ▸ | CDY1; CDY1B | Q9Y6F8 | 2/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL298688 | 0.83 | ALDH1A1 (0.38) | KDM4EACHEALDH1A1LMNAHPGD | |
| SCHEMBL662688 | 0.82 | ALDH1A1 (0.35) | KDM4EALDH1A1LMNAHPGDNPC1 | |
| SCHEMBL661116 | 0.80 | POLB (0.38) | ALDH1A1LMNAHPGDSMN1; SMN2HTT | |
| SCHEMBL660685 | 0.67 | ALDH1A1 (0.40) | KDM4EALDH1A1LMNAHPGDSMN1; SMN2 | |
| SCHEMBL9589188 | 0.65 | PTPN1 (0.59) | KDM4EALDH1A1LMNAHPGDSMN1; SMN2 | |
| SCHEMBL9936997 | 0.61 | HPGDS (0.50) | GPBAR1CYSLTR1 | |
| SCHEMBL4866787 | 0.61 | ACHE (0.67) | KDM4EACHEALDH1A1HPGDSMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL3842041 | 0.60 | ACHE (0.66) | KDM4EACHEALDH1A1NPC1PTPN1 | |
| SCHEMBL13426115 | 0.60 | SOD1 (0.49) | CYSLTR1 | |
| SCHEMBL9900670 | 0.60 | SMN1; SMN2 (0.45) | KDM4EALDH1A1SMN1; SMN2GRM5HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2427432-A2 | NOVEL HETEROCYCLIC COMPOUNDS | Torrent Pharmaceuticals Limited (IN) | 2012-03-14 | — | — | EP | disclosed |
| US-20120046317-A1 | NOVEL HETEROCYCLIC COMPOUNDS | DUTT CHAITANYA (IN) | 2012-02-23 | — | — | US | disclosed |
| WO-2010128528-A2 | NOVEL HETEROCYCLIC COMPOUNDS | TORRENT PHARMACEUTICALS LIMITED (IN) | 2010-11-11 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120046317-A1 | NOVEL HETEROCYCLIC COMPOUNDS | AGER, REN, AGT | GPBAR1 2906/4885KDM4E 2916/4885ACHE 356/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.