SCHEMBL2983407

SCHEMBL2983407

O=c1ccn(CCO)c(=O)[nH]1

nearest known ligand 0.59

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.57
LMNA P02545 1/20 0.57
L3MBTL1 Q9Y468 1/20 0.53
DUT P33316 11/20 0.51
CRBN Q96SW2 2/20 0.50
PKM P14618 1/20 0.49

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3079985 0.89 DUT (0.56) ALDH1A1LMNAL3MBTL1DUTCRBN
SCHEMBL4348697 0.87 L3MBTL1 (0.59) ALDH1A1LMNAL3MBTL1DUTCRBN
SCHEMBL913206 0.87 DUT (0.55) ALDH1A1LMNAL3MBTL1DUT
SCHEMBL24205032 0.85 NAAA (0.54) ALDH1A1LMNAL3MBTL1DUT
SCHEMBL913034 0.85 NAAA (0.54) ALDH1A1LMNAL3MBTL1DUT
SCHEMBL913371 0.85 NAAA (0.54) ALDH1A1LMNAL3MBTL1DUT
SCHEMBL25368590 0.85 NAAA (0.54) ALDH1A1LMNAL3MBTL1DUT
SCHEMBL28776122 0.84 L3MBTL1 (0.54) ALDH1A1LMNAL3MBTL1DUTCRBN
SCHEMBL338055 0.83 ALDH1A1 (0.56) ALDH1A1LMNAL3MBTL1DUTCRBN
SCHEMBL14861415 0.82 L3MBTL1 (0.54) ALDH1A1LMNAL3MBTL1DUTCRBN

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 47 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3157573-A2 ALTERNATIVE NUCLEIC ACID MOLECULES AND USES THEREOF Moderna Therapeutics, Inc. (US) 2017-04-26 EP claimed
WO-2015196128-A2 ALTERNATIVE NUCLEIC ACID MOLECULES AND USES THEREOF MODERNA THERAPEUTICS, INC. (US) 2015-12-23 WO claimed
EP-1019423-B1 METHOD FOR PRODUCING A PENTOPYRANOSYL NUCLEOSIDE NANOGEN RECOGNOMICS GMBH (DE) 2003-02-26 EP claimed
WO-2022155418-A9 MODIFIED OLIGONUCLEOTIDES ALNYLAM PHARMACEUTICALS, INC. (US) 2023-03-09 WO disclosed
WO-2023288047-A2 MULTIPLEXING TARGETING LIGANDS THROUGH CLICK CHEMISTRY AT THE ANOMERIC SITE OF SUGARS ALNYLAM PHARMACEUTICALS, INC. (US) 2023-01-19 WO disclosed
CN-108641092-B Preparation method of supramolecular polymer composite micelle based on hydrogen bond 辽宁大学 2021-06-18 CN disclosed
CN-109219665-A Method 牛津纳米孔技术公司 2019-01-15 CN disclosed
CN-109072225-A METHODS AND SYSTEMS FOR DETECTING TARGET NUCLEIC ACIDS 弗拉迪米尔.I.巴什基洛夫 2018-12-21 CN disclosed
CN-108884150-A Abrupt change hole 牛津纳米孔技术公司 2018-11-23 CN disclosed
CN-108779170-A Abrupt change hole 牛津纳米孔技术公司 2018-11-09 CN disclosed
CN-108699138-A Abrupt change hole 牛津纳米孔技术公司 2018-10-23 CN disclosed
EP-1034180-A2 LINKER NUCLEOSIDE, AND PRODUCTION AND USE OF THE SAME Nanogen Recognomics GmbH (DE) 2000-09-13 EP disclosed
EP-1019423-A2 METHOD FOR PRODUCING A PENTOPYRANOSYL NUCLEOSIDE Nanogen Recognomics GmbH (DE) 2000-07-19 EP disclosed
EP-1017703-A2 PENTOPYRANOSYL NUCLEOSIDE, AND PRODUCTION AND USE OF THE SAME Nanogen Recognomics GmbH (DE) 2000-07-12 EP disclosed
EP-1017704-A2 USE OF A PENTOPYRANOSYL NUCLEOSIDE CONTAINING CONJUGATE FOR PRODUCING AN ARRAY Nanogen Recognomics GmbH (DE) 2000-07-12 EP disclosed
WO-1999052923-A2 METHOD FOR THE PRODUCTION OF PENTOPYRANOSYL NUCLEOSIDES AVENTIS RESEARCH & TECHNOLOGIES GMBH & CO. KG (DE) 1999-10-21 WO disclosed
WO-1999015540-A2 METHOD FOR PRODUCING A PENTOPYRANOSYL NUCLEOSIDE AVENTIS RESEARCH & TECHNOLOGIES GMBH & CO KG (DE) 1999-04-01 WO disclosed
WO-1999015542-A2 LINKER NUCLEOSIDE, AND PRODUCTION AND USE OF THE SAME AVENTIS RESEARCH & TECHNOLOGIES GMBH & CO. KG (DE) 1999-04-01 WO disclosed
WO-1999015539-A2 PENTOPYRANOSYL NUCLEOSIDE, AND PRODUCTION AND USE OF THE SAME AVENTIS RESEARCH & TECHNOLOGIES GMBH & CO. KG (DE) 1999-04-01 WO disclosed
WO-1999015541-A2 USE OF A PENTOPYRANOSYL NUCLEOSIDE FOR PRODUCING AN ELECTRONIC COMPONENT, AND CONJUGATES OF SAID PENTOPYRANOSYL NUCLEOSIDE AVENTIS RESEARCH & TECHNOLOGIES GMBH & CO. KG (DE) 1999-04-01 WO disclosed